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TREM2

This shows microglia, neurons and plaques

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·March 10, 2020·4 min read

Stimulating immune cells to protect against Alzheimer’s

Stimulating activation of microglia may help eliminate Alzheimer's associated plaques, thus helping to prevent the progression of the neurodegenerative disease.

Featured Genetics Neurology Neuroscience

·July 11, 2019·4 min read

‘Crosstalk’ between genes promotes brain inflammation in Alzheimer’s

Findings could help in the development of treatments to prevent brain inflammation associated with Alzheimer's disease.

This shows amyloid beta, tau and microglia

Featured Genetics Neurology Neuroscience

·June 24, 2019·4 min read

Alzheimer’s missing link ID’d, answering what tips brain’s decline

Study in mice and humans reveals reinforcing the activity of microglia could slow, or potentially halt, the proliferation of Tau tangles in Alzheimer's disease.

This shows tyrobp expression in cells from the spinal cord in ALS

Featured Genetics Neurology Neuroscience

·April 7, 2019·5 min read

How ALS progresses on genetic and cellular level revealed by high-res spinal cord study

Changes in gene expression help researchers identify ALS associated pathways and establish the key drivers of motor neuron degeneration in the disease.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·March 29, 2019·5 min read

Researchers discover two, rare genes associated with Alzheimer’s disease

Two rare genetic variants on the NOTCH3 and TREM2 genes have been identified in some Alzheimer's patients.

Featured Genetics Neurology

·January 8, 2019·4 min read

Defective Immune Cells in Brain May Cause Alzheimer’s

Researchers report therapeutic activation of the TREM2 gene during the early stages of Alzheimer's disease may help to counteract the formation of amyloid beta protein aggregates.

Featured Neurology Neuroscience

·October 19, 2018·5 min read

Regulating Microglial Activity May Reduce Inflammation in Neurodegenerative Diseases

Researchers report activating microglia may help reduce the imbalance between neuroprotection and neurotoxicity for neurodegenerative diseases.

Featured Neurology Open Neuroscience Articles

·January 18, 2018·7 min read

Hits, Not Concussion, Cause CTE

A new study reveals head impact, not concussion, triggers CTE. The discovery could help with early detection and treatments for the neurodegenerative disorder.

Featured Neurology Neuroscience

·November 4, 2017·4 min read

Here’s What We Think Alzheimer’s Does to the Brain

A new paper explores different findings about the development of Alzheimer's and considers how personalized treatments may help combat this complex disease.

Featured Genetics Neurology Open Neuroscience Articles

·October 9, 2017·7 min read

Alzheimer’s Gene Poses Both Risks and Benefits

A new study from researchers at WUSTL reveals the TREM2 gene can have both positive and negative implications for the development of Alzheimer's disease and neuroinflammation.