Changes in gene expression help researchers identify ALS associated pathways and establish the key drivers of motor neuron degeneration in the disease.
Two rare genetic variants on the NOTCH3 and TREM2 genes have been identified in some Alzheimer's patients.
Researchers report therapeutic activation of the TREM2 gene during the early stages of Alzheimer's disease may help to counteract the formation of amyloid beta protein aggregates.
Researchers report activating microglia may help reduce the imbalance between neuroprotection and neurotoxicity for neurodegenerative diseases.
A new study reveals head impact, not concussion, triggers CTE. The discovery could help with early detection and treatments for the neurodegenerative disorder.
A new paper explores different findings about the development of Alzheimer's and considers how personalized treatments may help combat this complex disease.
A new study from researchers at WUSTL reveals the TREM2 gene can have both positive and negative implications for the development of Alzheimer's disease and neuroinflammation.
Researchers from Cardiff University have identified two new genes that can influence a person's risk of developing Alzheimer's disease.
Stimulating microglial cells could delay the onset of some neurodegenerative diseases, researchers report.
Findings may help to shed light on how Alzheimer's and other neurodegenerative diseases develop.
Researchers have discovered an early immune response in people with a genetic predisposition to Alzheimer's disease.
Researchers report the TREM2 mutation can derail the immune cell's plaque-clearing activity.