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TREM2

Featured Genetics Neurology Neuroscience

·July 11, 2019·4 min read

‘Crosstalk’ between genes promotes brain inflammation in Alzheimer’s

Findings could help in the development of treatments to prevent brain inflammation associated with Alzheimer's disease.

Featured Genetics Neuroscience Open Neuroscience Articles

·September 25, 2020·5 min read

A Genetic Variant That Protects Against Alzheimer’s Promotes Immune Cell Functions

PLCG2-P522R, a genetic variant that protects against Alzheimer's disease, enhances key functions of immune cells.

Image shows amyloid beta attacking a cell.

Featured Neurology

·June 15, 2016·8 min read

A New Role For Amyloid Beta in Alzheimer’s

Researchers have developed a new technique to measure levels of amyloid beta in the brain. They have also discovered new insights into why mutations of the TREM2 gene increases the risk of developing Alzheimer's disease.

Featured Genetics Neurology Open Neuroscience Articles

·October 9, 2017·7 min read

Alzheimer’s Gene Poses Both Risks and Benefits

A new study from researchers at WUSTL reveals the TREM2 gene can have both positive and negative implications for the development of Alzheimer's disease and neuroinflammation.

This shows amyloid beta, tau and microglia

Featured Genetics Neurology Neuroscience

·June 24, 2019·4 min read

Alzheimer’s missing link ID’d, answering what tips brain’s decline

Study in mice and humans reveals reinforcing the activity of microglia could slow, or potentially halt, the proliferation of Tau tangles in Alzheimer's disease.

Featured Genetics Neurology Neuroscience

·March 9, 2021·6 min read

CBD Reduces Plaque and Improves Cognition in Model of Familial Alzheimer’s

A two-week course of CBD helps normalize and restore the function of two proteins associated with reducing amyloid-beta accumulation in mouse models of familial Alzheimer's disease. CBD also reduces levels of IL-6, an immune protein associated with inflammation in Alzheimer's patients.

Featured Genetics Neurology

·January 8, 2019·4 min read

Defective Immune Cells in Brain May Cause Alzheimer’s

Researchers report therapeutic activation of the TREM2 gene during the early stages of Alzheimer's disease may help to counteract the formation of amyloid beta protein aggregates.

Featured Neurology Open Neuroscience Articles

·March 7, 2016·3 min read

Does A ‘Western Diet’ Increase Alzheimer’s Risk?

Having a sedentary lifestyle and eating a western diet is linked to an increased risk of developing Alzheimer's disease, a new study reports.

Diagram shows how TREM2 attaches to neurons.

Featured Neurology Open Neuroscience Articles

·March 5, 2016·5 min read

Early Biomarkers for Alzheimer’s Defined

Researchers have identified a biomarker that is associated with the activation of an innate immune response to neural damage during the early stages of Alzheimer's disease.

Featured Neurology

·December 14, 2016·4 min read

Early Signs of Alzheimer’s Detected in Cerebrospinal Fluid

Researchers have discovered an early immune response in people with a genetic predisposition to Alzheimer's disease.

the image shows an MRI scan of an Alzheimer's patient who carries the TERM2 genetic mutation.

Featured Genetics

·October 18, 2013·3 min read

Genetic Mutation Linked to Alzheimer’s Disease Doubles Rate of Brain Tissue Loss

Carries of the TREM2 genetic mutation associated with Alzheimer's disease could develop the disease up to three years earlier than expected, a new study finds.

Featured Genetics Neurology Neuroscience

·September 30, 2024·5 min read

Genetic Variants Linked to Alzheimer’s Trigger Inflammation in Females

Researchers have discovered that two genetic variants, APOE4 and TREM2 R47H, together cause a harmful inflammatory response in brain immune cells, particularly in females. This response leads to more severe brain damage, including tau protein clumps, which are linked to Alzheimer’s disease progression.

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TREM2

‘Crosstalk’ between genes promotes brain inflammation in Alzheimer’s

A Genetic Variant That Protects Against Alzheimer’s Promotes Immune Cell Functions

A New Role For Amyloid Beta in Alzheimer’s

Alzheimer’s Gene Poses Both Risks and Benefits

Alzheimer’s missing link ID’d, answering what tips brain’s decline

CBD Reduces Plaque and Improves Cognition in Model of Familial Alzheimer’s

Defective Immune Cells in Brain May Cause Alzheimer’s

Does A ‘Western Diet’ Increase Alzheimer’s Risk?

Early Biomarkers for Alzheimer’s Defined

Early Signs of Alzheimer’s Detected in Cerebrospinal Fluid

Genetic Mutation Linked to Alzheimer’s Disease Doubles Rate of Brain Tissue Loss

Genetic Variants Linked to Alzheimer’s Trigger Inflammation in Females

Cannabis Destroys Sleep Quality

Genetic Risk for Anorexia May Begin Outside the Brain

Higher BMI Linked to Longer Survival After a Dementia Diagnosis

Can We Predict Hearing Loss Long Before Symptoms Ever Start?

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