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          TREM2

          This shows a woman's head and a brain.
          FeaturedGeneticsNeurologyNeuroscience
          ·September 30, 2024·5 min read

          Genetic Variants Linked to Alzheimer’s Trigger Inflammation in Females

          Researchers have discovered that two genetic variants, APOE4 and TREM2 R47H, together cause a harmful inflammatory response in brain immune cells, particularly in females. This response leads to more severe brain damage, including tau protein clumps, which are linked to Alzheimer’s disease progression.
          Read More
          This shows a brain
          FeaturedNeurologyNeuroscience
          ·June 7, 2022·3 min read

          Rapamycin Increases Alzheimer’s-Associated Plaques in Mice

          Rapamycin, a drug approved for the treatment of cancer and transplant patients increases amyloid-beta protein plaques in the brains of mice.
          Read More
          This shows a diagram from the study
          FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles
          ·March 23, 2022·4 min read

          How TREM2 Gene Mutation in Brain Microglia Immune Cells Can Increase Alzheimer’s Risk

          A molecular process caused by the TREM2 gene mutation in the brain's microglia increases the risk of Alzheimer's disease, a new study reports.
          Read More
          This shows a brain
          FeaturedGeneticsNeurologyNeuroscience
          ·February 14, 2022·3 min read

          How a Gene Variant Protects Against Alzheimer’s

          The P522R gene variant increases expression levels of several microglia genes which are reduced in people with Alzheimer's disease.
          Read More
          This is a diagram from the study
          FeaturedGeneticsNeurologyNeuroscience
          ·January 9, 2022·3 min read

          Research Clears up How Brain ‘Cleaners’ Fail in ALS

          Findings point to microglial TREM2 as a potential target for the treatment of ALS.
          Read More
          This shows single cell RNA sequencing of the microglia response in a mouse model of Alzheimer's
          FeaturedGeneticsNeurologyNeuroscience
          ·December 1, 2021·4 min read

          Targeting the Brain’s Immune Cells May Help Prevent Alzheimer’s Disease

          A drug currently being tested in cancer clinical trials appears to prevent dysfunction in an immune cell signaling pathway associated with Alzheimer's disease. Blocking the pathway could prevent Alzheimer's from developing and slow the progression of symptoms for those who already have the disease.
          Read More
          This shows a brain
          FeaturedNeurologyNeuroscienceOpen Neuroscience Articles
          ·August 26, 2021·3 min read

          Inflammatory Proteins Help Better Diagnose Progression of Alzheimer’s Disease

          Testing for specific inflammatory proteins in cerebrospinal fluid can help doctors to diagnose the early onset of Alzheimer's disease and track the progression of the disease in patients.
          Read More
          This shows a purple brain
          FeaturedGeneticsNeurologyNeuroscience
          ·March 9, 2021·6 min read

          CBD Reduces Plaque and Improves Cognition in Model of Familial Alzheimer’s

          A two-week course of CBD helps normalize and restore the function of two proteins associated with reducing amyloid-beta accumulation in mouse models of familial Alzheimer's disease. CBD also reduces levels of IL-6, an immune protein associated with inflammation in Alzheimer's patients.
          Read More
          This shows DNA
          FeaturedGeneticsNeuroscienceOpen Neuroscience Articles
          ·September 25, 2020·5 min read

          A Genetic Variant That Protects Against Alzheimer’s Promotes Immune Cell Functions

          PLCG2-P522R, a genetic variant that protects against Alzheimer's disease, enhances key functions of immune cells.
          Read More
          This shows a brain
          FeaturedNeurologyOpen Neuroscience Articles
          ·August 7, 2020·4 min read

          Key to Dialogue Between Brain Cells to Protect Against Stroke Discovered

          DHA treatment reduced the size of the damaged brain area and initiated a repair mechanism in animal models of stroke. DHA affected the levels of MANF and TREM2, two proteins critical for communication between brain cells.
          Read More
          This shows microglia, neurons and plaques
          FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles
          ·March 10, 2020·4 min read

          Stimulating immune cells to protect against Alzheimer’s

          Stimulating activation of microglia may help eliminate Alzheimer's associated plaques, thus helping to prevent the progression of the neurodegenerative disease.
          Read More
          This shows a DNA strand
          FeaturedGeneticsNeurologyNeuroscience
          ·July 11, 2019·4 min read

          ‘Crosstalk’ between genes promotes brain inflammation in Alzheimer’s

          Findings could help in the development of treatments to prevent brain inflammation associated with Alzheimer's disease.
          Read More
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          This shows an ear.

          Gene Therapy Restores Hearing in Those with Deafness

          This shows a brain.

          Forever Chemicals May Disrupt Brain Development

          This shows kids playing games.

          Kids Outsmart AI in Puzzle Game That Builds Critical Thinking

          This shows a neuron.

          Drug-Coated Neural Implants Reduce Immune Rejection

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