Inducing gamma oscillations with visual stimulation via a process known as gamma entrainment using sensory stimuli, or GENUS, was shown to reduce amyloid plaques and phosphorylated tau in mouse models of dementia. Providing GENUS daily during the early stages of neurodegeneration helps preserve neural and synaptic density across multiple brain areas and improves cognitive performance for learning and spatial memory tasks. Read More
A new two-tier diagnostic blood test which evaluates both amyloid beta and tau, can help detect Alzheimer's disease in presymptomatic patients. Read More
Self-propagating amyloid and tau act as prions in the pathology of Alzheimer's disease. Higher levels of the prions in human brain samples were strongly correlated with early onset of Alzheimer's and death at a younger age. Read More
PET imaging of former NFL players who exhibited cognitive decline and psychiatric symptoms linked to CTE showed higher levels of tau in areas of the brain associated with the neurodegenerative disease. Read More
Study reinforces and explains the links between sleep deprivation and neurodegenerative diseases, researchers say. Read More
Researchers report they have identified biomarkers of Alzheimer's disease in spinal fluid samples of a significant number of older patients hospitalized as a result of hip fractures. The study suggests neural alterations that lead to poor balance in older people may signify an increased risk of falls that result in hip fractures, and Alzheimer's disease. Researchers suggest the hip fracture, therefore, may serve as an early sign of Alzheimer's in older patients. Read More
A new study reports sleep deprivation increases the levels of tau, and accelerates the spread of the protein, in the brain. The findings reveal a lack of sleep alone may help drive the development of Alzheimer's disease. Read More
A new mouse study reveals males recall fearful memories better than females. Researchers attribute the difference to the gene Cdk5, which has previously been implicated in creating fear memories and stress behaviors. The study reports Cdk5 is naturally activated in males, but not females. Read More
A new study reports leaky capillaries in the brain may be an early sign of Alzheimer's disease as it can signal cognitive impairment prior to the buildup of proteins associated with the neurodegenerative disease. Read More
A new study links poor sleep quality in older adults with elevated levels of tau, a protein associated with Alzheimer's disease. Researchers report poor sleep quality later in life may be associated with declining brain health and may be an early indicator of Alzheimer's disease. Read More
Researchers report excitatory neurons are more vulnerable to accumulations of Tau, a protein implicated in Alzheimer's disease. Read More
Study reports a mutation in a single gene that causes hereditary frontotemporal dementia makes it harder for neurons to communicate, leading to neurodegeneration. Read More