FeaturedGeneticsNeurologyNeuroscience·September 15, 2019How the eyes might be windows to the risk of Alzheimer’s diseaseAdults with mild cognitive impairment (MCI), a precursor to Alzheimer's disease, have greater pupil dilation when taking cognitive tests than their cognitively normal peers. Task-evoked pupillary response may be a cost-effective, and low invasive screening test for those at genetic risk for Alzheimer's before the symptoms of the disease take hold. Read More
FeaturedNeurologyNeuroscience·August 12, 2019Alzheimer’s disease destroys neurons that keep us awakeTau accumulations disrupt wake-promoting neurons. The findings help explain why day-time napping and sleep disruptions are often reported in Alzheimer's patients. Read More
FeaturedNeurologyNeuroscienceNeuroscience Videos·August 7, 2019Routine hits playing football cause damage to the brainSustained hits following one season of playing football are enough to cause structural alterations to the brain. When players sustain a concussion, structural brain integrity decreases, and levels of tau increase. Researchers say, while concussions are a prime concern for those who play football, sustained hits also pose a threat to neurological health. Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·August 1, 2019Super-resolution microscopy sheds light on how dementia protein becomes dysfunctionalA microscopy study revealed tau controls Fyn clustering in dendrites. The findings shed new light on how certain forms of dementia may occur. Read More
FeaturedNeuroscience·July 31, 2019Novel discovery of links between liver dysfunction and Alzheimer’s diseaseA link between liver dysfunction and Alzheimer's disease has been discovered. The findings add to the understanding of the role metabolic dysfunction plays in the neurodegenerative disease. Read More
FeaturedNeurologyNeuroscience·July 16, 2019Risk and progression of Alzheimer’s disease differ by genderThe risk of developing Alzheimer's disease is increased, and progression more rapid in women due to larger brain-wide accumulation and acceleration in the spread of tau. Read More
FeaturedGeneticsNeurologyNeuroscience·July 9, 2019Sorting protein in neurons defends against neurodegenerative diseaseVPS35 is a novel critical component of tau metabolism and the pathology of neurodegenerative diseases. Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·July 8, 2019Indications why older people are more susceptible to Alzheimer’s diseaseUsing a gene vector, researchers channeled the blueprint of the human tau protein into different aged mice. After a period of twelve weeks, the tau protein spread twice as fast in older mice than the younger cohort. Findings shed light on why Alzheimer's is predominantly an age-related neurodegenerative disease. Read More
FeaturedNeurologyNeuroscience·June 27, 2019Disrupted sleep in one’s 50s, 60s raises risk of Alzheimer’s diseaseSleep disruptions during middle age may be a potential biomarker for developing Alzheimer's disease later in life. Researchers found those who experienced sleep problems in their 40s and 50s had more amyloid beta accumulation in their brains later in life. Those whose sleep problems started in their 50s and 60s had increased levels of tau. Additionally, higher levels of tau were discovered in the brains of those who lacked synchronized brain waves associated with a good night's sleep. Read More
FeaturedGeneticsNeurologyNeuroscience·June 24, 2019Alzheimer’s missing link ID’d, answering what tips brain’s declineStudy in mice and humans reveals reinforcing the activity of microglia could slow, or potentially halt, the proliferation of Tau tangles in Alzheimer's disease. Read More
FeaturedGeneticsNeurologyNeuroscience·June 24, 2019Alzheimer’s disease: Sex affects tau accumulation in the brainWomen with the ApoE e4 genetic risk factor for Alzheimer's are more susceptible to tau accumulation in the brain than men. Read More
FeaturedNeurologyNeuroscience·June 17, 2019Sleep history predicts late-life Alzheimer’s pathologyYour sleep history during middle age may predict Alzheimer's pathology later in life. A decrease in sleep quality between 50 and 70 years of age is associated with higher levels of tau and amyloid beta in the brain. Changes in brain activity and quality of sleep could be a biomarker for Alzheimer's disease. Read More
