The protein beta-arrestin-2 increases tau tangle accumulation in Alzheimer's disease and frontotemporal dementia but interfering with the removal of excess tau from the brain.
Cognitive performance may predict the progression from normal to abnormal levels of Alzheimer's associated amyloid-beta.
Study finds significant expression of the Alzheimer's related Tau protein in glioma cells, especially in patients with better prognoses.
Following a night of sleep deprivations, levels of tau in the blood increase 17% in healthy young men.
Genomic autism-related ADNP mutations were found in postmortem olfactory bulbs and hippocampi of Alzheimer's patients.
Extra virgin olive oil may protect against cognitive declines linked to tauopathy diseases, specifically frontotemporal dementia.
The NLPR3 inflammasome and the inflammatory response it triggers play a critical role in the emergence of tau pathology.
Tau buildup associated with Alzheimer's disease is not, in itself, harmful, but the cellular process it disrupts kills neurons.
For those with mild cognitive impairment (MCI) and other risk factors for Alzheimer's disease, participating in aerobic exercise several times a week may slow neurodegeneration. Aerobic exercise reduced hippocampal atrophy in those with MCI.
Adults with mild cognitive impairment (MCI), a precursor to Alzheimer's disease, have greater pupil dilation when taking cognitive tests than their cognitively normal peers. Task-evoked pupillary response may be a cost-effective, and low invasive screening test for those at genetic risk for Alzheimer's before the symptoms of the disease take hold.
Tau accumulations disrupt wake-promoting neurons. The findings help explain why day-time napping and sleep disruptions are often reported in Alzheimer's patients.
Sustained hits following one season of playing football are enough to cause structural alterations to the brain. When players sustain a concussion, structural brain integrity decreases, and levels of tau increase. Researchers say, while concussions are a prime concern for those who play football, sustained hits also pose a threat to neurological health.
