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Tau

·April 12, 2021·5 min read

Imbalance in Gum Bacteria Linked to Alzheimer’s Disease Biomarker

An increase in bad gum bacteria and a decrease in good bacteria is associated with amyloid-beta in cerebral spinal fluid samples of older adults. The findings add to the growing body of evidence linking periodontal disease to the development of Alzheimer's.

Featured Genetics Neurology Neuroscience

·April 9, 2021·3 min read

Aluminum Is Intricately Associated With the Neuropathology of Familial Alzheimer’s Disease

Study reveals aluminum is co-located with the tau protein in people with familial Alzheimer's disease.

This shows an outline of a woman's head, brain and birds flowing in it

Featured Neurology Neuroscience

·March 25, 2021·4 min read

Women Accumulate Alzheimer’s-Related Protein Faster

Study reports tau accumulation in the temporal lobe was 75% higher in women than men.

Featured Genetics Neurology Open Neuroscience Articles

·March 19, 2021·3 min read

Gene Therapy Using ‘Zinc Fingers’ May Help Treat Alzheimer’s Disease

A new genetic engineering strategy significantly reduces levels of tau in animal models of Alzheimer's disease. The treatment, which involves a single injection, appears to have long-last effects.

Featured Neurology Neuroscience

·February 17, 2021·4 min read

SuperAger Brains Resist Protein Tangles That Lead to Alzheimer’s

SuperAgers who maintain their cognitive abilities have resistance to the development of Alzheimer's related tau tangles. The resistance to tangles may help to preserve memory.

This is a computer reimaging of how tau affects a neuron

Featured Neurology Neuroscience

·February 2, 2021·2 min read

New Discovery for How the Brain ‘Tangles’ in Alzheimer’s Disease

Study identifies a new "seeding" process in neurons that could be a cause of dementia and Alzheimer's disease.

Featured Neurology Neuroscience

·February 2, 2021·4 min read

Automated Imaging Detects and Tracks Brain Protein Involved in Alzheimer’s Disease

A new automated method can identify and track the development of tau deposits in the brain. The method could lead to an earlier diagnosis of Alzheimer's disease.

Featured Neurology Neuroscience

·October 12, 2020·3 min read

Brain Regions With Impaired Blood Flow Have Higher Tau Levels

Impaired blood flow to specific areas of the brain coincides with Tau buildup in Alzheimer's patients. As cognition declines, the relationship between vascular dysfunction and Tau accumulation strengthens.

This shows the outline of a person's head

Featured Genetics Neurology Open Neuroscience Articles

·September 15, 2020·4 min read

Heroin-Addicted Individuals Have Unique Brain Disturbances Resembling Those of Alzheimer’s

Altered expression of FYN, a gene associated with the production of Tau, was identified in the brains of people addicted to heroin. Findings suggest opioid use can affect the brain in a way that might cause vulnerability in neural systems that can trigger neurodegeneration later in life.

Featured Neurology

·September 1, 2020·4 min read

Estrogen Replacement May Protect Against Alzheimer’s Disease in Women

Early postmenopausal estrogen replacement therapy may protect some women from developing Alzheimer's disease.

This shows a head with a pencil erasing it

Featured Neurology

·July 28, 2020·4 min read

Alzheimer’s Protein in Blood Indicates Early Brain Changes

Blood samples taken from people enrolled in an Alzheimer's research study revealed higher levels of phosphorylated tau 217 that correlated with the presence of amyloid plaques. People with amyloid in their brains had up to three times more of the tau protein in their blood than those who had no evidence of amyloid accumulation. The higher levels of the protein were evident even in people with no signs of cognitive decline.