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Tau

·June 14, 2021·3 min read

A New Model of Alzheimer’s Progression

A new model of Alzheimer's progression highlights the link between glial cells, toxic protein buildup, and neurodegeneration.

Featured Genetics Neurology Neuroscience

·May 19, 2021·6 min read

New Insight Into Protein Production in Brain Could Help Tackle Dementia

Researchers have identified a layer of genetic material involved in controlling the production of tau in the brain. The material is part of a larger family of non-coding genes that regulate and control other brain proteins associated with neurodegenerative disorders, such as Alzheimer's disease, Parkinson's, and PSP. The findings could lead to the development of new therapeutics to treat a range of neurodegenerative disorders.

Featured Neurology Neuroscience

·May 16, 2021·4 min read

Anesthetic May Affect Tau Spread in the Brain to Promote Alzheimer’s Disease Pathology

Sevoflurane, an anesthetic, causes tau to leave neurons and enter microglia. This stimulates the production of interleukin-6, leading to inflammation and cognitive impairment.

Featured Neurology Neuroscience

·May 5, 2021·3 min read

Does Eating a Mediterranean Diet Protect Against Memory Loss and Dementia?

Eating a Mediterranean-style diet can help protect the brain from tau protein build-up and brain shrinkage associated with Alzheimer's disease.

Featured Neurology Neuroscience

·April 29, 2021·5 min read

Alzheimer’s Disease Is Composed of Four Distinct Subtypes

Researchers have identified four distinct subtypes of Alzheimer's disease. The findings could lead to more individualized treatments for those with the neurodegenerative disorder.

Featured Neurology Neuroscience Open Neuroscience Articles

·April 20, 2021·5 min read

Chaperone Protein Imbalance Promotes Toxic Tau Buildup in the Aging Brain

A new preclinical study has identified the role chaperone protein imbalance plays in initiating the accumulation of tau in the brain.

Featured Neurology Neuroscience

·April 12, 2021·5 min read

Imbalance in Gum Bacteria Linked to Alzheimer’s Disease Biomarker

An increase in bad gum bacteria and a decrease in good bacteria is associated with amyloid-beta in cerebral spinal fluid samples of older adults. The findings add to the growing body of evidence linking periodontal disease to the development of Alzheimer's.

Featured Genetics Neurology Neuroscience

·April 9, 2021·3 min read

Aluminum Is Intricately Associated With the Neuropathology of Familial Alzheimer’s Disease

Study reveals aluminum is co-located with the tau protein in people with familial Alzheimer's disease.

This shows an outline of a woman's head, brain and birds flowing in it

Featured Neurology Neuroscience

·March 25, 2021·4 min read

Women Accumulate Alzheimer’s-Related Protein Faster

Study reports tau accumulation in the temporal lobe was 75% higher in women than men.

Featured Genetics Neurology Open Neuroscience Articles

·March 19, 2021·3 min read

Gene Therapy Using ‘Zinc Fingers’ May Help Treat Alzheimer’s Disease

A new genetic engineering strategy significantly reduces levels of tau in animal models of Alzheimer's disease. The treatment, which involves a single injection, appears to have long-last effects.

Featured Neurology Neuroscience

·February 17, 2021·4 min read

SuperAger Brains Resist Protein Tangles That Lead to Alzheimer’s

SuperAgers who maintain their cognitive abilities have resistance to the development of Alzheimer's related tau tangles. The resistance to tangles may help to preserve memory.