FeaturedNeurology·July 15, 2020·4 min readSuper-Agers Show Resistance to Tau and Amyloid AccumulationPET neuroimaging reveals super-agers and those whose cognitive skills are above the norm for an advanced age have an increased resistance to tau and amyloid proteins.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·May 29, 2020·2 min readHow toxic protein spreads in Alzheimer’s diseaseTau spreads through the human brain via neural communication pathways. The spread is accelerated by the presence of amyloid-beta.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·March 18, 2020·5 min readAlzheimer’s risk genes converge on microgliaFindings indicate a large part of the genetic risk of Alzheimer's involves a microglial response to amyloid-beta.Read More
AutismFeaturedGeneticsNeuroscience·March 2, 2020·4 min readCould targeting an Alzheimer’s-associated protein prevent Autism?Reducing levels of the Alzheimer's related Tau protein prevents autism-like behaviors in mouse models. Tau reduction also prevented seizures in the animals.Read More
FeaturedNeurologyNeuroscience·February 17, 2020·4 min readBeta-arrestin-2 increases neurotoxic tau driving frontotemporal dementiaThe protein beta-arrestin-2 increases tau tangle accumulation in Alzheimer's disease and frontotemporal dementia but interfering with the removal of excess tau from the brain.Read More
FeaturedGeneticsNeurologyNeuroscience·February 14, 2020·4 min readSubtle decline in cognition predicts progression to Alzheimer’s pathologyCognitive performance may predict the progression from normal to abnormal levels of Alzheimer's associated amyloid-beta.Read More
Brain CancerFeaturedNeurologyNeuroscienceOpen Neuroscience Articles·January 23, 2020·2 min readUnexpected connection between gliomas and neurodegenerative diseasesStudy finds significant expression of the Alzheimer's related Tau protein in glioma cells, especially in patients with better prognoses.Read More
FeaturedNeurologyNeuroscience·January 11, 2020·4 min readLosing a night of sleep may increase blood levels of Alzheimer’s biomarkerFollowing a night of sleep deprivations, levels of tau in the blood increase 17% in healthy young men.Read More
AutismFeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·November 26, 2019·4 min readAutism-related genetic mutations occur in aging brains of Alzheimer’s patientsGenomic autism-related ADNP mutations were found in postmortem olfactory bulbs and hippocampi of Alzheimer's patients.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·November 25, 2019·5 min readStudy shows extra virgin olive oil staves off multiple forms of dementia in miceExtra virgin olive oil may protect against cognitive declines linked to tauopathy diseases, specifically frontotemporal dementia.Read More
FeaturedNeurologyNeuroscience·November 20, 2019·4 min readInflammatory processes drive progression of Alzheimer’s and other brain diseasesThe NLPR3 inflammasome and the inflammatory response it triggers play a critical role in the emergence of tau pathology.Read More
FeaturedNeurologyNeuroscience·October 28, 2019·2 min readHow Alzheimer’s disease spreads through the brainTau buildup associated with Alzheimer's disease is not, in itself, harmful, but the cellular process it disrupts kills neurons.Read More
