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Tau

·February 2, 2021·4 min read

Automated Imaging Detects and Tracks Brain Protein Involved in Alzheimer’s Disease

A new automated method can identify and track the development of tau deposits in the brain. The method could lead to an earlier diagnosis of Alzheimer's disease.

Featured Neurology Neuroscience

·October 12, 2020·3 min read

Brain Regions With Impaired Blood Flow Have Higher Tau Levels

Impaired blood flow to specific areas of the brain coincides with Tau buildup in Alzheimer's patients. As cognition declines, the relationship between vascular dysfunction and Tau accumulation strengthens.

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Featured Genetics Neurology Open Neuroscience Articles

·September 15, 2020·4 min read

Heroin-Addicted Individuals Have Unique Brain Disturbances Resembling Those of Alzheimer’s

Altered expression of FYN, a gene associated with the production of Tau, was identified in the brains of people addicted to heroin. Findings suggest opioid use can affect the brain in a way that might cause vulnerability in neural systems that can trigger neurodegeneration later in life.

Featured Neurology

·September 1, 2020·4 min read

Estrogen Replacement May Protect Against Alzheimer’s Disease in Women

Early postmenopausal estrogen replacement therapy may protect some women from developing Alzheimer's disease.

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Featured Neurology

·July 28, 2020·4 min read

Alzheimer’s Protein in Blood Indicates Early Brain Changes

Blood samples taken from people enrolled in an Alzheimer's research study revealed higher levels of phosphorylated tau 217 that correlated with the presence of amyloid plaques. People with amyloid in their brains had up to three times more of the tau protein in their blood than those who had no evidence of amyloid accumulation. The higher levels of the protein were evident even in people with no signs of cognitive decline.

Autism Featured Neurology Open Neuroscience Articles

·July 28, 2020·5 min read

Experimental Drug for Alzheimer’s May Help Children With Autism

Children suffering from a form of autism called ADNP syndrome may benefit from an experimental drug designed to treat Alzheimer's disease.

Featured Neurology

·July 15, 2020·4 min read

Super-Agers Show Resistance to Tau and Amyloid Accumulation

PET neuroimaging reveals super-agers and those whose cognitive skills are above the norm for an advanced age have an increased resistance to tau and amyloid proteins.

Featured Neurology Neuroscience Open Neuroscience Articles

·May 29, 2020·2 min read

How toxic protein spreads in Alzheimer’s disease

Tau spreads through the human brain via neural communication pathways. The spread is accelerated by the presence of amyloid-beta.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·March 18, 2020·5 min read

Alzheimer’s risk genes converge on microglia

Findings indicate a large part of the genetic risk of Alzheimer's involves a microglial response to amyloid-beta.

Autism Featured Genetics Neuroscience

·March 2, 2020·4 min read

Could targeting an Alzheimer’s-associated protein prevent Autism?

Reducing levels of the Alzheimer's related Tau protein prevents autism-like behaviors in mouse models. Tau reduction also prevented seizures in the animals.

Featured Neurology Neuroscience

·February 17, 2020·4 min read

Beta-arrestin-2 increases neurotoxic tau driving frontotemporal dementia

The protein beta-arrestin-2 increases tau tangle accumulation in Alzheimer's disease and frontotemporal dementia but interfering with the removal of excess tau from the brain.