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Tau

·August 12, 2019·5 min read

Alzheimer’s disease destroys neurons that keep us awake

Tau accumulations disrupt wake-promoting neurons. The findings help explain why day-time napping and sleep disruptions are often reported in Alzheimer's patients.

Featured Neurology Neuroscience Neuroscience Videos

·August 7, 2019·6 min read

Routine hits playing football cause damage to the brain

Sustained hits following one season of playing football are enough to cause structural alterations to the brain. When players sustain a concussion, structural brain integrity decreases, and levels of tau increase. Researchers say, while concussions are a prime concern for those who play football, sustained hits also pose a threat to neurological health.

Featured Neurology Neuroscience Open Neuroscience Articles

·August 1, 2019·3 min read

Super-resolution microscopy sheds light on how dementia protein becomes dysfunctional

A microscopy study revealed tau controls Fyn clustering in dendrites. The findings shed new light on how certain forms of dementia may occur.

Featured Neuroscience

·July 31, 2019·6 min read

Novel discovery of links between liver dysfunction and Alzheimer’s disease

A link between liver dysfunction and Alzheimer's disease has been discovered. The findings add to the understanding of the role metabolic dysfunction plays in the neurodegenerative disease.

This shows an old couple walking down a country lane

Featured Neurology Neuroscience

·July 16, 2019·2 min read

Risk and progression of Alzheimer’s disease differ by gender

The risk of developing Alzheimer's disease is increased, and progression more rapid in women due to larger brain-wide accumulation and acceleration in the spread of tau.

Featured Genetics Neurology Neuroscience

·July 9, 2019·4 min read

Sorting protein in neurons defends against neurodegenerative disease

VPS35 is a novel critical component of tau metabolism and the pathology of neurodegenerative diseases.

Featured Neurology Neuroscience Open Neuroscience Articles

·July 8, 2019·3 min read

Indications why older people are more susceptible to Alzheimer’s disease

Using a gene vector, researchers channeled the blueprint of the human tau protein into different aged mice. After a period of twelve weeks, the tau protein spread twice as fast in older mice than the younger cohort. Findings shed light on why Alzheimer's is predominantly an age-related neurodegenerative disease.

This shows a brain with tau deposits marked

Featured Neurology Neuroscience

·June 27, 2019·8 min read

Disrupted sleep in one’s 50s, 60s raises risk of Alzheimer’s disease

Sleep disruptions during middle age may be a potential biomarker for developing Alzheimer's disease later in life. Researchers found those who experienced sleep problems in their 40s and 50s had more amyloid beta accumulation in their brains later in life. Those whose sleep problems started in their 50s and 60s had increased levels of tau. Additionally, higher levels of tau were discovered in the brains of those who lacked synchronized brain waves associated with a good night's sleep.

This shows amyloid beta, tau and microglia

Featured Genetics Neurology Neuroscience

·June 24, 2019·4 min read

Alzheimer’s missing link ID’d, answering what tips brain’s decline

Study in mice and humans reveals reinforcing the activity of microglia could slow, or potentially halt, the proliferation of Tau tangles in Alzheimer's disease.

Featured Genetics Neurology Neuroscience

·June 24, 2019·2 min read

Alzheimer’s disease: Sex affects tau accumulation in the brain

Women with the ApoE e4 genetic risk factor for Alzheimer's are more susceptible to tau accumulation in the brain than men.

This shows brain scans of the hippocampus during sleep

Featured Neurology Neuroscience

·June 17, 2019·3 min read

Sleep history predicts late-life Alzheimer’s pathology

Your sleep history during middle age may predict Alzheimer's pathology later in life. A decrease in sleep quality between 50 and 70 years of age is associated with higher levels of tau and amyloid beta in the brain. Changes in brain activity and quality of sleep could be a biomarker for Alzheimer's disease.

Featured Neurology Neuroscience

·June 17, 2019·4 min read

Antioxidant puts up fight, but loses battle against protein linked to Alzheimer’s disease

During early Alzheimer's disease, SOD1 initially weakens levels of Tau protein. However, as the disease progresses, the antioxidant becomes less effective at protecting the brain against neurodegeneration.

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Tau

Alzheimer’s disease destroys neurons that keep us awake

Routine hits playing football cause damage to the brain

Super-resolution microscopy sheds light on how dementia protein becomes dysfunctional

Novel discovery of links between liver dysfunction and Alzheimer’s disease

Risk and progression of Alzheimer’s disease differ by gender

Sorting protein in neurons defends against neurodegenerative disease

Indications why older people are more susceptible to Alzheimer’s disease

Disrupted sleep in one’s 50s, 60s raises risk of Alzheimer’s disease

Alzheimer’s missing link ID’d, answering what tips brain’s decline

Alzheimer’s disease: Sex affects tau accumulation in the brain

Sleep history predicts late-life Alzheimer’s pathology

Antioxidant puts up fight, but loses battle against protein linked to Alzheimer’s disease

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