Latest

synaptic plasticity

·August 22, 2012·6 min read

Low-dose Sedative Alleviates Autistic-like Behavior in Mice with Dravet Syndrome Mutation

A low dose of the sedative clonazepam alleviated autistic-like behavior in mice with a mutation that causes Dravet syndrome in humans.

Featured Neuroscience

·August 8, 2012·4 min read

Simple Mathematical Computations Underlie Brain Circuits

Neuroscientists report that two major classes of brain cells repress neural activity in specific mathematical ways: One type subtracts from overall activation, while the other divides it.

Featured Neuroscience

·August 8, 2012·4 min read

New Model Synapse Could Shed Light on Disorders Such as Epilepsy and Anxiety

A new way to study the role of a critical neurotransmitter in disorders such as epilepsy, anxiety, insomnia, depression, schizophrenia, and alcohol addiction has been developed. This model synapse can precisely control a variety of receptors for the neurotransmitter called GABA, which is important in brain chemistry.

Featured Neurology Psychology

·August 6, 2012·8 min read

Brain Signal IDs Responders to Fast-Acting Antidepressants

Scientists have discovered a biological marker that may help to identify which depressed patients will respond to an experimental, rapid-acting antidepressant like ketamine. The brain signal, detectable by noninvasive imaging, also holds clues to the agent's underlying mechanism, which are vital for drug development, say NIH researchers.

Featured Genetics Neuroscience

·August 6, 2012·4 min read

Brain’s Stem Cells Eavesdrop to Find Out When to Act

Working with mice, Johns Hopkins researchers say they have figured out how stem cells found in a part of the brain responsible for learning, memory and mood regulation decide to remain dormant or create new brain cells. Apparently, the stem cells “listen in” on the chemical communication among nearby neurons to get an idea about what is stressing the system and when they need to act.

Featured Neuroscience

·August 1, 2012·4 min read

Brain Imaging Can Predict How Intelligent You Are, Study Finds

Research from Washington University in St. Louis suggests that another 10 percent of individual differences in intelligence can be explained by the strength of neural pathways connecting the left lateral prefrontal cortex to the rest of the brain.

Electrophysiology Featured Neuroscience

·July 26, 2012·2 min read

Ion Selectivity in Neuronal Signaling Channels Evolved Twice in Animals

Scientists have now revealed that voltage-gated sodium channels, which are responsible for neuronal signaling in the nerves of animals, evolved twice in higher and lower animals.

Electrophysiology Featured Neuroscience

·July 12, 2012·10 min read

Large, Medically Important Class of Proteins Starts to Yield Its Secrets

Five recent research papers shed light on elusive G protein-coupled receptors. New techniques and insights used to solve the GPCR structures are discussed.

Electrophysiology Featured Psychology

·July 11, 2012·7 min read

Why the Thrill is Gone: Scientists Identify Potential Target for Treating Major Symptom of Depression

Scientists have laid bare a novel molecular mechanism responsible for the major depression symptom, anhedonia, the loss of the ability to experience pleasure. The brain circuit involved in this newly elucidated pathway is largely identical between rodents and humans, upping the odds that the findings point toward new therapies for depression and other disorders. Additionally, opinion leaders hailed the study’s inventive methodology, saying it may offer a much sounder approach to testing new antidepressants.

Featured Neurology Neuroscience Business

·July 10, 2012·4 min read

Nutrient Mixture Improves Memory in Patients with Early Alzheimer’s

A clinical trial of an Alzheimer’s disease treatment developed found that the nutrient cocktail can improve memory in patients with early Alzheimer’s. The mixture appears to increase the number of dendritic spines and therefore some synapses.