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synapses

Brain Cancer Featured Genetics Neurology Neuroscience

·January 30, 2020·5 min read

Brain tumors remodel neuronal synapses to promote growth

Several variants of the PIK3CA gene drive brain tumor progression. Two of the variants alter the expression of genes involved in synapses.

Featured Neuroscience Open Neuroscience Articles

·January 25, 2020·4 min read

Shaping the social networks of neurons

Researchers have identified a protein complex that both attracts and repels neurons during brain development.

Autism Featured Genetics Neuroscience

·January 23, 2020·4 min read

Largest autism genetics study identifies 102 associated genes

In the largest genetic sequencing study of autism conducted to date, researchers have identified 102 genes associated with the neurodevelopmental disorder. 49 of the genes were also associated with other developmental delays. The new study has enabled the researchers to increase the number of ASD associated genes from 65 to 102.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·January 14, 2020·4 min read

Study finds evidence for reduced brain connections in schizophrenia

Neuroimaging study reveals decreased levels of the SV2A protein in synapses in patients with schizophrenia. The decrease in the protein could underlie the cognitive difficulties experienced by those with schizophrenia and provide new targets for treatment.

This shows a drawing of a rat and brain cells

Featured Neuroscience

·December 6, 2019·4 min read

Dendrites filtering neuron’s excitement

Purkinje cells can modulate and filter incoming signals. The findings shed new light on learning mechanisms within the cerebellum.

Autism Featured Genetics Neuroscience

·December 6, 2019·3 min read

How gene mutation causes autism and intellectual disability

Genetic mutations in Usp9X results in the brain growing fewer synapses during development. The mutation also causes hyperactivity and an increased risk of anxiety. The findings shed new light on the cause of autism and other intellectual disabilities.

This shows synapses images as part of this study

Featured Genetics Neuroscience Open Neuroscience Articles

·September 29, 2019·5 min read

Technique can image individual proteins within synapses

A new rapid imaging technique allows researchers to view synaptic proteins at high resolution.

Featured Genetics Neuroscience Psychology

·September 23, 2019·4 min read

Gene regulators work together for oversized impact on schizophrenia risk

Using CRISPR to alter the expression of four schizophrenia implicated genes which harbor expression quantitative trait loci, researchers were able to mirror gene expression changes seen in postmortem brains of those suffering from three mental health disorders.

This shows faces made up of network lines

Featured Neuroscience Open Neuroscience Articles

·September 13, 2019·4 min read

Opiates reduce the brain’s ability to form and maintain synapses

Opiate exposure causes synaptic rewiring in the nucleus accumbens in addition to decreasing dendritic spines. The findings shed light into the neurobiology of opiate relapse.

Featured Neuroscience Open Neuroscience Articles Visual Neuroscience

·September 13, 2019·4 min read

New insights into how astrocytes help the brain process information

Noradrenaline is essential for astrocytes to respond to local stimulation.

Featured Neurology Neuroscience

·September 4, 2019·4 min read

‘Hunger Hormone’ Linked to Memory in Alzheimer’s Study

A study that used postmortem brain tissue samples from Alzheimer's patients and mouse models found the hunger hormone ghrelin is linked to cognitive impairments and memory loss associated with the disease.

Featured Neurology Neuroscience Open Neuroscience Articles

·August 30, 2019·4 min read

Blue Brain finds how neurons in the mouse neocortex form billions of synaptic connections

Scientists generated statistical instances of the micro-connectome, containing over 10 million neurons. The model spans five orders of magnitude and contains 88 billion synaptic connections.

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