Study identifies the main components driving amyloid beta-associated synaptic degeneration.
Thrombospondin-2, a protein with cell adhesion properties usually secreted by astrocytes, prompted a strong increase in synapses in male-derived neurons but showed no effect in females.
Study sheds new light on the role noncoded RNAs play at the synapse.
A new whole-genome sequencing study has revealed thirteen novel genes associated with Alzheimer's disease. Researchers also found a new link between Alzheimer's and synaptic function.
Findings shed new light on how the brain wires during development.
A new theory of memory visualizes the brain as an organic super-computer that runs complex binary code with neurons acting like mechanical computers. The theory is based on the discovery of the protein molecule, talin, which contains switch-like domains that change shape in response to pressure in mechanical force by a cell.
Over-expression of the synaptic protein RAPGEF2 drives synaptic loss associated with Alzheimer's disease.
Prolonged anesthesia significantly alters the synaptic architecture of the brain, regardless of age.
A newly developed light-activated protein allows researchers to study single synapses of a neuron.
Gray matter damage associated with multiple sclerosis progression may be caused by inflammatory reactions that lead to synaptic loss.
Using a snap-freezing method, researchers have been able to reveal the true structure of the connections that join neurons together in the adult brain.
Researchers have developed a novel approach to measure the activity and strength of individual synapses that drive a neuron's response to sensory input.
