Latest

stem cells

The image shows Newborn neurons in the brain of a 3 month old mouse.

·February 7, 2013·3 min read

Dickkopf Makes Fountain of Youth in the Brain Run Dry

Scientists have discovered that significantly more neurons are generated in the brains of older animals if the signaling molecule Dickkopf-1 is turned off. The results give rise to the question whether the function of Dickkopf-1 may be turned off using drugs to prevent age related cognitive decline.

The image shows the gut nervous system. The caption explains the image best.

Featured Genetics

·February 1, 2013·5 min read

How Deficiencies in Two Genes Synergize to Halt Formation of Gut Nervous System

Researchers identify a new gene associated with Hirschprung Disease and show how the migration of cells that form the gut nervous system is impeded when the combined doses of two candidate genes are low. Understanding the genetic basis of HSCR offers hope for better diagnostics and treatment for it and other developmental defects caused by failure of cell migration.

The image shows the cell nuclei in human embryonic stem cells.

Featured Genetics

·January 22, 2013·3 min read

Stem Cell Research Aims to Help Identify Origins of Schizophrenia

New research demonstrates how defects in an important neurological pathway in early development may be responsible for the onset of schizophrenia later in life.

Featured Neuroscience

·January 21, 2013·3 min read

Researchers Turn One Form of Neuron into Another in the Brain

A new finding turns one of the basics of neurobiology on its head, demonstrating that it is possible to turn one type of already differentiated neuron into another within the brain.

Featured Neuroscience

·October 26, 2012·2 min read

Stimulating Brain Cells with Light

The work will be conducted on laboratory rats modelling Parkinson’s disease. The transplanted cells will be derived from skin from an adult human and will have been “reprogrammed” as nerve cells. The light-sensitive protein is obtained from a bacterium, which uses light to gain energy.

Neurons are shown. Caption describes it well.

Brain Cancer Featured Neurology

·October 22, 2012·3 min read

Aggressive Brain Tumors Can Originate from a Range of Nervous System Cells

Scientists have long believed that glioblastoma multiforme, the most aggressive type of primary brain tumor, begins in glial cells that make up supportive tissue in the brain or in neural stem cells. Researchers found that the tumors can originate from other types of differentiated cells in the nervous system, including cortical neurons.

Featured Genetics Neuroscience

·August 9, 2012·5 min read

Neuroscientists Find Brain Stem Cells that May Be Responsible for Higher Functions, Bigger Brains

A neuron’s fate was thought to be determined by the timing of its birth date. Neuroscientists recently showed that there is a distinct stem cell progenitor that gives rise to upper layer neurons, regardless of birth date or place.

Featured Genetics Neuroscience

·August 6, 2012·4 min read

Brain’s Stem Cells Eavesdrop to Find Out When to Act

Working with mice, Johns Hopkins researchers say they have figured out how stem cells found in a part of the brain responsible for learning, memory and mood regulation decide to remain dormant or create new brain cells. Apparently, the stem cells “listen in” on the chemical communication among nearby neurons to get an idea about what is stressing the system and when they need to act.

Brain Cancer Featured Genetics Neurology

·August 1, 2012·2 min read

Study Suggests New Treatment Target for Deadly Brain Tumors

“We identified a subset of brain tumor cells that are slower growing or remain at rest, and appear to be the source of cancer recurrence after standard therapy in which the drug temozolomide is given to stop the tumor’s growth,” said Dr. Luis Parada. “Current therapy targets fast-growing tumor cells but not those responsible for new tumors. To the best of our knowledge, this is the first identification of a cancer stem-like cell in a spontaneously forming tumor inside a mammal.”

Autism Featured Psychology

·July 17, 2012·4 min read

Researchers Find Evidence of Link between Immune Irregularities and Autism

A new Caltech study suggests that specific changes in an overactive immune system can indeed contribute to autism-like behaviors in mice, and that in some cases, this activation can be related to what a developing fetus experiences in the womb.

Featured Genetics Neuroscience

·July 16, 2012·3 min read

Neurons Derived from Cord Blood Cells May Represent New Therapeutic Option

The researchers demonstrated that cord blood cells, which come from the mesoderm, the middle layer of embryonic germ cells, can be switched to ectodermal cells, outer layer cells from which brain, spinal and nerve cells arise. "This study shows for the first time the direct conversion of a pure population of human cord blood cells into cells of neuronal lineage by the forced expression of a single transcription factor," says Juan Carlos Izpisua Belmonte.

Genetics

·June 7, 2012·3 min read