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stem cells

This shows cells from a cerebral organoid

Featured Genetics Neuroscience Neuroscience Videos

·January 30, 2020·6 min read

Not ‘brains in a dish’: Cerebral organoids flunk comparison to developing nervous system

Hailed by many as a breakthrough for neuroscience research, a new study reports brain-in-a-dish models may not be as useful as reported previously. The study reports instead of differentiating normally into the brain's distinctive cell types, cerebral organoids often express mixed genes normally found in different kinds of cells.

Autism Featured Genetics Neuroscience

·January 30, 2020·4 min read

Study links rapid brain growth in autism to DNA damage

Neural progenitor cells generated from skin cell samples of people on the autism spectrum had heightened levels of DNA damage. The damage clustered in 36 of the same genes which had also been damaged in healthy cells exposed to replication stress. Twenty of the genes have previously been linked to the development of autism.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·January 29, 2020·4 min read

New injection technique may boost spinal cord injury repair efforts

Researchers have developed a new method for delivering neural precursor cells into rat models of spinal cord injury. The method is safe, effective, and reduces the likelihood of further spinal trauma while delivering larger doses of reparative stem cells. The new approach could also be used for the treatment of ALS and multiple sclerosis.

Featured Genetics Neurology Neuroscience

·January 27, 2020·5 min read

Parkinson’s disease may start before birth

10% of patients diagnosed with Parkinson's disease are between the ages of 21 and 50. For those with young-onset Parkinson's disease, researchers report the foundations for the disease may have been apparent before they were born. The study also points to a drug, currently approved to treat precancerous skin growths, that has the potential to reduce elevated levels of alpha-synuclein.

Featured Genetics Neurology Neuroscience Pain

·January 25, 2020·2 min read

First treatment for pain using human stem cells a success

Transplanting GABAergic cells derived from human-induced pluripotent stem cells into mice resulted in safe, lasting, and effective relief from extreme neuropathic pain. Researchers hope to begin human testing within five years.

Featured Genetics Neuroscience Psychology

·January 22, 2020·5 min read

How stress causes gray hair

Study reveals a link between the nervous system and stem cells that regenerate pigment in hair follicles. When stressed, norepinephrine from the sympathetic nervous system causes melanocyte stem cells to activate excessively. The stem cells all convert into pigment-producing cells, prematurely depleting the reservoir. The findings explain the cellular and molecular links between stress and premature hair graying.

Featured Genetics Neuroscience

·January 20, 2020·2 min read

A new role for neurogenesis

Dentate gyrus neurogenesis acts to replace lost neurons and restore function following massive neuron loss.

Electrophysiology Featured Genetics Neuroscience Open Neuroscience Articles

·January 9, 2020·4 min read

Rejuvenating the brain: More stem cells improve learning and memory of old mice

Critical aspects of hippocampal function can be reversed in old age, or compensated for throughout life, with the help of neural stem cells.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·September 16, 2019·5 min read

Transplanted brain stem cells survive without anti-rejection drugs

Researchers have developed a new method to transplant neural stem cells into mice without the need for lifelong anti-rejection medications.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·September 16, 2019·4 min read

Alzheimer’s disease risk gene APOE4 impairs function of brain immune cells

APOE4 increases the inflammatory response of human microglia while reducing cellular migration. The gene also impairs the metabolic activity of the immune cells. The findings show APOE4 has a profound impact on the basic functions of microglia.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·September 14, 2019·4 min read

Scientists identify gene as master regulator in schizophrenia

TCF4 may serve as a master regulator of a gene network dysregulated in schizophrenia at the early stages of neurodevelopment.

Featured Genetics Neurology Neuroscience

·August 30, 2019·4 min read

Creation of new brain cells plays an underappreciated role in Alzheimer’s disease

Microglia may play a significant role in disrupting neurogenesis in those with Alzheimer's disease. When mice were given drugs which caused microglial cells to die, neurogenesis returned to normal.

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stem cells

Not ‘brains in a dish’: Cerebral organoids flunk comparison to developing nervous system

Study links rapid brain growth in autism to DNA damage

New injection technique may boost spinal cord injury repair efforts

Parkinson’s disease may start before birth

First treatment for pain using human stem cells a success

How stress causes gray hair

A new role for neurogenesis

Rejuvenating the brain: More stem cells improve learning and memory of old mice

Transplanted brain stem cells survive without anti-rejection drugs

Alzheimer’s disease risk gene APOE4 impairs function of brain immune cells

Scientists identify gene as master regulator in schizophrenia

Creation of new brain cells plays an underappreciated role in Alzheimer’s disease

How Scientists Cracked the Ketamine Code for Depression

Brain Prioritizes “Sound Offsets” During Hearing Repair

Glucose Levels Signal the Growth of Myelin

Why Your Brain “Dreams” Even When You’re Awake

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