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stem cells

Featured Genetics Neurology Neuroscience

·June 17, 2019·3 min read

Stem cells reprogrammed into neurons could reveal drugs harmful to pregnancy

A new experimental system which uses embryonic stem cells reprogrammed into neurons has the potential to assess the pathogenic effects of a drug on brain development.

Featured Genetics Neurology Neuroscience

·June 5, 2019·3 min read

Nanotechnology treatment reverses multiple sclerosis in mice

Extracting nanosized exosomes from bone marrow stem cells and injecting them into mice, researchers reverse symptoms of multiple sclerosis.

Featured Genetics Neuroscience Open Neuroscience Articles

·May 31, 2019·4 min read

Intranasal stem cell therapy restores smell in mice

The sense of smell has been restored to mice suffering olfactory problems with the aid of stem cell therapies. The findings provide the basis for transitional research to see whether intranasal stem cell treatments can be beneficial for those who have lost their sense of smell.

Brain Cancer Featured Neurology Neuroscience Open Neuroscience Articles

·May 30, 2019·4 min read

Pairing of glutamine-targeting drug and ketogenic diet fights glioblastoma in mice

Combining an antibiotic drug that targets glutamine with the ketogenic diet helps kill glioblastoma cancer cells, reversing symptoms of the disease and improving survivability in mouse models.

Featured Genetics Neuroscience

·May 23, 2019·3 min read

Targeting key gene could help lead to down syndrome treatment

Using stem cells from candidates with Down syndrome to create an organoid, and employing mouse models, researchers pinpoint a gene linked to memory impairments and cognitive problems in Down syndrome. Inhibiting the OLIG2 gene leads to cognitive and memory improvements in mouse models of Down. Researchers hope their findings lead to an in utero treatment that targets the gene and helps reverse abnormal brain development.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·May 6, 2019·5 min read

Pigment-producing stem cells can regenerate myelin sheath: Mouse study

Skin-related stem cells may be key to helping restore the myelin sheath in patients with multiple sclerosis. Using mouse models, researchers discovered melanocyte stem cells can, under the right conditions, function as cells that create myelin.

Featured Genetics Neurology Neuroscience

·May 1, 2019·5 min read

Restoring brain function in mice with symptoms of Alzheimer’s disease

Senolytic drugs administered to mice reduced senescent cells around amyloid plaques by more than 90% and decreased neuroinflammation by 50%. Mice treated with the drug combination also showed improvements in spatial memory, compared to other Alzheimer's model mice who received no treatment. The findings could have positive implications for the treatment of Alzheimer's disease in people with the condition.

Featured Genetics Neuroscience Open Neuroscience Articles

·April 24, 2019·3 min read

Proteins stand up to nerve cell regression

Study reveals the critical and novel roles Integrator complex proteins play in promoting healthy brain development in flies.

Brain Cancer Featured Genetics Neuroscience Open Neuroscience Articles

·April 16, 2019·4 min read

Scientists ‘reverse engineer’ brain cancer cells to find new targets for treatment

Using CRISPR-Cas9 gene editing, researchers identified actionable pathways responsible for the growth of glioblastoma stem cells. By reverse engineering brain cancer cells, multiple potential new targets for cancer treatments have been uncovered.

Featured Genetics Neuroscience Open Neuroscience Articles

·April 16, 2019·3 min read

Researchers discover crucial link between brain and gut stem cells

The insulin-like growth factor II gene plays a critical role in adult stem cell maintenance of both the intestine and the brain. Findings suggest IGF-2 is essential for multiple stem cell types, including those implicated in cognitive function and renewing the lining of the small intestine.

Featured Genetics Neurology Neuroscience

·April 5, 2019·3 min read

Parkinson’s clues seen in tiny fish could aid quest for treatments

Zebrafish study reveals how key dopaminergic neurons, which are damaged as a result of Parkinson's disease, can be regenerated. Researchers report the immune system plays a critical role in the process.