Fruit fly study reveals suppression of a genetic switch boosts long-term memory.
Researchers have identified a set of drug-like compounds, including a common ingredient in throat lozenges, that can help protect mitochondria from the stresses associated with neurodegenerative diseases.
The severity of Charcot-Marie-Tooth disease is linked to the degree to which the aminoacyl-tRNA synthetases enzyme is relaxed or extended.
Exosomes carry signaling information required to regulate neural circuit development.
Levels of a key molecule are elevated in the amygdala of both humans and mouse models of PTSD. The microRNA, mir-135b-5p, may be a novel biomarker for treating the disorder.
PPL2 neurons help modulate the strength of memories.
Researchers genetically restored levels of the SynGAP protein in adult mice who were deficient. Restoring the protein levels resulted in improved memory and a reduction in seizures related to the SYNGAP1 disorder, a form of autism. Findings suggest it is possible to extend the window of treatment for those with this specific form of ASD, beyond infancy and into adulthood.
Optogenetic inactivation of CRF neurons in the central nucleus of the amygdala decreases escalation of alcohol consumption and intensity of withdrawal in rodent models of alcoholism. The findings suggest a potential target for treating excessive drinking in alcohol use disorder.
Researchers have engineered a new enzyme that breaks down nicotine in the bloodstream before it reaches the brain. The treatment reduces the urge to smoke and reverses signs of nicotine dependence, preventing relapse.
Activating a receptor found in neurons in the habenula could help treat alcohol addiction and ease withdrawal symptoms, researchers report.
Researchers shed new light on neuroplasticity by sparking learning in tadpole brains. They discovered the key to neuroplasticity is how the brain generates new proteins. Findings could help deepen understanding of sensory processing in ASD.
Scripps researchers have uncovered the process that helps control neuron growth.
