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Scripps Research Institute

·March 28, 2020·3 min read

FDA approves ozanimod for treatment of multiple sclerosis

The FDA has approved a new drug named Ozanimod for the treatment of multiple sclerosis. Ozanimod binds to receptors in lymphocytes' surfaces, preventing them from reaching the brain. As the number of active lymphocytes decreases, the attack on the immune system diminishes.

Featured Genetics Neuroscience

·January 13, 2020·2 min read

Long-term memory performance depends upon gating system

Fruit fly study reveals suppression of a genetic switch boosts long-term memory.

Electrophysiology Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·January 12, 2020·4 min read

Neurons’ energy organelle protected from damage linked to ALS & Alzheimer’s

Researchers have identified a set of drug-like compounds, including a common ingredient in throat lozenges, that can help protect mitochondria from the stresses associated with neurodegenerative diseases.

Featured Genetics Neurology Neuroscience

·September 30, 2019·4 min read

‘Relaxed’ enzymes may be at the root of Charcot-Marie-Tooth disease

The severity of Charcot-Marie-Tooth disease is linked to the degree to which the aminoacyl-tRNA synthetases enzyme is relaxed or extended.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·July 22, 2019·4 min read

Exosomes may hold the answer to treating and diagnosing developmental brain disorders

Exosomes carry signaling information required to regulate neural circuit development.

Featured Genetics Neuroscience Psychology

·June 19, 2019·4 min read

Overcoming PTSD: Study reveals memory disruption drug target

Levels of a key molecule are elevated in the amygdala of both humans and mouse models of PTSD. The microRNA, mir-135b-5p, may be a novel biomarker for treating the disorder.

Featured Neuroscience Open Neuroscience Articles

·May 14, 2019·4 min read

Unexplored neural circuit modulates memory strength: Fruit fly study

PPL2 neurons help modulate the strength of memories.

Featured Genetics Neuroscience

·April 26, 2019·4 min read

Gene repair improves memory and seizures in adult autism model

Researchers genetically restored levels of the SynGAP protein in adult mice who were deficient. Restoring the protein levels resulted in improved memory and a reduction in seizures related to the SYNGAP1 disorder, a form of autism. Findings suggest it is possible to extend the window of treatment for those with this specific form of ASD, beyond infancy and into adulthood.

Featured Neuroscience Open Neuroscience Articles

·March 18, 2019·5 min read

Scientists hunt down the brain circuit responsible for alcohol cravings

Optogenetic inactivation of CRF neurons in the central nucleus of the amygdala decreases escalation of alcohol consumption and intensity of withdrawal in rodent models of alcoholism. The findings suggest a potential target for treating excessive drinking in alcohol use disorder.

Featured Neuroscience Open Neuroscience Articles

·October 17, 2018·5 min read

Engineered Enzyme Eliminates Nicotine Addiction in Preclinical Tests

Researchers have engineered a new enzyme that breaks down nicotine in the bloodstream before it reaches the brain. The treatment reduces the urge to smoke and reverses signs of nicotine dependence, preventing relapse.

Featured Neuroscience

·June 26, 2018·6 min read

A New Way to Block Alcohol Addiction and Ease Withdrawal Discovered

Activating a receptor found in neurons in the habenula could help treat alcohol addiction and ease withdrawal symptoms, researchers report.

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·May 3, 2018·5 min read

Wriggling Tadpoles May Hold Clues to How Autism Develops

Researchers shed new light on neuroplasticity by sparking learning in tadpole brains. They discovered the key to neuroplasticity is how the brain generates new proteins. Findings could help deepen understanding of sensory processing in ASD.

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Scripps Research Institute

FDA approves ozanimod for treatment of multiple sclerosis

Long-term memory performance depends upon gating system

Neurons’ energy organelle protected from damage linked to ALS & Alzheimer’s

‘Relaxed’ enzymes may be at the root of Charcot-Marie-Tooth disease

Exosomes may hold the answer to treating and diagnosing developmental brain disorders

Overcoming PTSD: Study reveals memory disruption drug target

Unexplored neural circuit modulates memory strength: Fruit fly study

Gene repair improves memory and seizures in adult autism model

Scientists hunt down the brain circuit responsible for alcohol cravings

Engineered Enzyme Eliminates Nicotine Addiction in Preclinical Tests

A New Way to Block Alcohol Addiction and Ease Withdrawal Discovered

Wriggling Tadpoles May Hold Clues to How Autism Develops

LLMs and Math Combine to Map Human Decision-Making

Sleep Apnea’s Main Symptom Is Also its Cause

Zero-Computational Path to High-Resolution Robotic Touch

Zebrafish Brain Features Mammalian-Like Sensory Sorting

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