Scripps Research Institute

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Scripps Research Institute

·April 26, 2019·4 min read

Gene repair improves memory and seizures in adult autism model

Researchers genetically restored levels of the SynGAP protein in adult mice who were deficient. Restoring the protein levels resulted in improved memory and a reduction in seizures related to the SYNGAP1 disorder, a form of autism. Findings suggest it is possible to extend the window of treatment for those with this specific form of ASD, beyond infancy and into adulthood.

Featured Neuroscience Open Neuroscience Articles

·March 27, 2022·5 min read

Scientists Hunt for Neurons Responsible for Alcohol Withdrawal

Researchers reveal the role corticotropin-releasing factor produced by neurons plays in alcohol withdrawal symptoms.

Featured Genetics Neurology Open Neuroscience Articles

·September 16, 2020·4 min read

New Gene Implicated in ALS and Other Motor Neuron Diseases

A defective protein quality control system leads to motor neuron death associated with disorders like ALS.

This shows proteins in the retinal cells

Featured Neuroscience

·January 31, 2022·4 min read

A New Type of Cellular Communication in the Brain

Researchers have identified hundreds of proteins that are consistently transported throughout the healthy brain via small membrane-enclosed sacs. The findings reveal a new form of communication between brain cells.

Featured Neuroscience Open Neuroscience Articles

·November 22, 2016·4 min read

Scientists Find Surprising Answers to ‘Food Coma’ Conundrum

Researchers believe they may have found a reason for that all too well known holiday phenomenon, a 'food coma'.

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·April 15, 2020·5 min read

Autism in males linked to defect in brain immune cells and microglia

An over-production of eIF4E impairs microglial cells, hampering their ability to effectively prune synapses and leading to autism-like behaviors in male mouse models of ASD.

Featured Genetics Neuroscience

·June 22, 2022·4 min read

Scientists Identify Sensor Underlying Mechanical Itch Stimulus

Study identifies a specific protein in sensory neurons that detects mechanical itch stimuli such as an insect crawling on the skin or when one touches an object that irritates the skin.

Featured Neuroscience Open Neuroscience Articles

·November 22, 2017·5 min read

To Forget or to Remember? Memory Depends on Subtle Brain Signals

Study reveals how the mechanism for storing olfactory memories differs slightly from erasing unnecessary memories. Understanding how the brain gets rid of unimportant memories could help unlock new avenues of research to better understand memory loss in aging, researchers say.

Electrophysiology Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·January 12, 2020·4 min read

Neurons’ energy organelle protected from damage linked to ALS & Alzheimer’s

Researchers have identified a set of drug-like compounds, including a common ingredient in throat lozenges, that can help protect mitochondria from the stresses associated with neurodegenerative diseases.