The severity of Charcot-Marie-Tooth disease is linked to the degree to which the aminoacyl-tRNA synthetases enzyme is relaxed or extended.
Scripps researchers have uncovered the process that helps control neuron growth.
Researchers have identified hundreds of proteins that are consistently transported throughout the healthy brain via small membrane-enclosed sacs. The findings reveal a new form of communication between brain cells.
Activating a receptor found in neurons in the habenula could help treat alcohol addiction and ease withdrawal symptoms, researchers report.
A new study reports reduced levels of Rheb result in memory loss in animal models of dementia.
Exposure to anesthesia causes lipid clusters to move from an ordered state to a disordered one, then back again. These changes lead to subsequent effects that cause changes in consciousness.
An over-production of eIF4E impairs microglial cells, hampering their ability to effectively prune synapses and leading to autism-like behaviors in male mouse models of ASD.
Study reveals how two neural circuits dictate the choice between social approach and avoidance. The network connecting the infralimbic cortex to the basolateral amygdala (BLA) impairs social behavior if there is a decrease in neural activity. Another network connecting the prelimbic cortex to the BLA similarly impairs social behavior if the neural activity is increased.
A new advanced imaging technique shows how cholesterol regulates the production of Alzheimer's associated amyloid beta proteins in astrocytes.
Those with PTSD are almost twice as likely to develop alcohol use disorder than their peers who have not experienced trauma. Researchers report drugs that block FKBP5, such as benztropine, a drug used to control symptoms of Parkinson's disease, and the experimental compound SAFit2 reduce alcohol preference and drinking in models of PTSD.
Researchers have determined the near-atomic scale structure of the anxiety-associated GPR158 receptor. The findings enable an avenue to create potential therapeutics to block the receptor in order to treat depression, stress, and other mental health disorders.
Researchers report neurons in areas of the brain associated with memory formation can form networks in the absence of synaptic activity.
