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Parkinson’s disease

Featured Neurology Neuroscience Psychology

·March 4, 2024·4 min read

How Impulse Control Disorders Alter Processing of Risky Decisions

A novel study explores how Parkinson's disease patients, particularly those with impulse control disorders (ICD) induced by dopaminergic medications, process the outcomes of risky decisions.

Featured Neurology Neuroscience

·February 23, 2024·6 min read

Mapping the Brain’s ‘Dysfunctome’

Researchers achieved a breakthrough in mapping the brain's 'dysfunctome'—key dysfunctional circuits linked to disorders like Parkinson’s, dystonia, OCD, and Tourette’s syndrome. Utilizing deep brain stimulation (DBS) data from 261 patients worldwide, they pinpointed specific frontal cortex circuits crucial for symptom improvement.

Featured Genetics Neurology Neuroscience

·January 8, 2024·5 min read

Novel Gene Linked to Range of Neurodegenerative Diseases Identified

Researchers uncovered a crucial link between the gene Angiogenin (ANG) and age-related neurodegenerative diseases such as frontotemporal dementia (FTD), motor neuron disease (MND), and Parkinson's disease. In its mutated form, ANG causes stem cells to delay their differentiation into specialized nerve cells, leading to neurodevelopmental defects.

Featured Neurology Neuroscience

·January 5, 2024·5 min read

Soft Robotic Garment Defeats Parkinson’s Freezing

Researchers deploy a soft, wearable robot to combat freezing, a common and debilitating symptom of Parkinson's disease. The robot, worn around the hips and thighs, provides a gentle push during leg swings, helping patients achieve longer strides.

Featured Neurology Neuroscience

·December 5, 2023·5 min read

Dopaminergic System Organoid Model Illuminates Parkinson’s and Addiction

Researchers developed a novel organoid model that mimics the human dopaminergic system, providing crucial insights into Parkinson's disease and the impact of chronic cocaine use. This study demonstrates the model's ability to replicate the structure, connectivity, and functionality of the dopaminergic system.

Featured Neurology Neuroscience

·November 21, 2023·4 min read

Used Coffee Grounds Hold Potential Key to Treating Neurodegenerative Diseases

Researchers found that Carbon Quantum Dots (CACQDs) derived from used coffee grounds could protect brain cells from damage caused by neurodegenerative diseases like Alzheimer's and Parkinson's. CACQDs showed neuroprotective effects in various models, including Parkinson's caused by pesticide exposure. These CACQDs have the potential to address the underlying causes of neurodegenerative disorders, rather than just managing symptoms.

Featured Neurology Neuroscience

·November 15, 2023·4 min read

Parkinson’s Progression Halted by Inhibiting Enzyme

Researchers discovered that inhibiting a specific enzyme, USP30, in a mouse model protects dopamine-producing neurons, which are typically lost as the disease progresses. This groundbreaking finding suggests a new therapeutic avenue that could slow or even prevent Parkinson's progression.

Featured Genetics Neurology Neuroscience

·October 5, 2023·5 min read

Caffeine Cuts Parkinson’s, Even with Genetic Predisposition

New research unveils a significant correlation between caffeine consumption and a lowered risk of Parkinson’s Disease (PD) for individuals with Asian gene variants linked to the disorder. The study involving 4,488 subjects disclosed that regular consumption of tea or coffee curtailed the risk of developing PD by four to eight times compared to non-caffeine drinkers who have the gene.

Featured Neurology Neuroscience

·September 29, 2023·4 min read

Circadian Rhythm Off Beat: Parkinson’s and Nighttime Neuron Damage

Researchers delved into the enigma of sleep disturbances and their relation to Parkinson's disease. Utilizing fruit flies, they found that cellular stress linked to Parkinson's was especially damaging to neurons during nighttime.

Featured Neurology Neuroscience

·September 15, 2023·6 min read

Parkinson’s Onset Theory Challenged: Synaptic Dysfunction Before Neuron Death

Contrary to the widely held belief that Parkinson’s disease originates from the degeneration of dopaminergic neurons, a new study suggests a precursor: synaptic dysfunction. This revelation unveils the dysfunction of dopaminergic synapses prior to neurodegeneration.

Featured Neurology Neuroscience

·September 7, 2023·4 min read

Glymphatic System Key to Parkinson’s Protein Spread and Aggregation

Researchers shed light on the puzzle of Parkinson’s disease progression. They discovered that a mutated version of the α-synuclein protein moves through the brain's lymphatic system, known as the glymphatic system, before aggregating.

Featured Genetics Neurology Neuroscience

·August 30, 2023·9 min read

Could A Gene Be A Hidden Shield Against Alzheimer’s & Parkinson’s?

Researchers identified a gene allele, known as DR4, that offers more than a 10% average reduction in the risk of Alzheimer's and Parkinson's diseases. The study, involving hundreds of thousands of people from various ancestries, suggests a potential role of the tau protein in both conditions.