Latest

Parkinson’s disease

·June 18, 2024·6 min read

Blood Test Predicts Parkinson’s Years Before Symptoms

Researchers have developed an AI-powered blood test that can predict Parkinson's disease up to seven years before symptoms appear. The test analyzes eight blood biomarkers and has shown 100% accuracy in diagnosing the disease. This breakthrough offers the potential for early intervention and treatment before significant damage occurs in the brain.

Featured Genetics Neurology Neuroscience

·June 18, 2024·5 min read

Vitamin B Deficiency in Gut Linked to Parkinson’s

A new study reveals a link between gut bacteria and Parkinson's disease (PD). Researchers found a decrease in genes responsible for synthesizing essential B vitamins in PD patients, which may weaken the intestinal barrier and lead to inflammation in the brain. This finding suggests that B vitamin supplementation could be a potential therapeutic avenue for PD.

Brain Cancer Featured Neurology Neuroscience

·June 17, 2024·5 min read

Cancer Drug May Halt Parkinson’s Spread

Researchers discovered a novel therapeutic target for Parkinson's disease, the Aplp1 protein, which facilitates the spread of harmful alpha-synuclein proteins in the brain. Notably, an FDA-approved cancer drug targeting Lag3, a protein that interacts with Aplp1, has shown promise in blocking this spread in mouse models.

Featured Neurology Neuroscience

·May 30, 2024·5 min read

Age-Linked Sympathetic Denervation Worsens PD Non-Motor Symptoms

Researchers found that Parkinson’s disease (PD) patients with sympathetic denervation in major salivary glands and the heart exhibit more severe non-motor symptoms as they age. This research highlights the importance of age in PD progression and could enhance the understanding of the disease's pathophysiology.

Featured Neurology Neuroscience

·May 28, 2024·4 min read

Caffeine Intake Doesn’t Slow Parkinson’s Progression

A new study examined the impact of caffeine on brain dopamine function in Parkinson's patients, finding no benefits on disease progression. High caffeine consumption was linked to a greater decrease in dopamine transporter binding, likely due to a compensatory mechanism rather than neuron loss.

Featured Genetics Neurology Neuroscience

·April 30, 2024·4 min read

Enhancing Neurogenesis for Parkinson’s Treatment

Researchers have pioneered a method to enhance the generation of dopaminergic neurons, crucial for Parkinson’s disease treatment, by targeting specific receptors within the Wnt signaling pathway. Using synthetic antibodies, the team successfully directed stem cell differentiation in the midbrain to produce these key neurons, which are instrumental in brain health and depleted in Parkinson’s patients.

Featured Neurology Neuroscience Visual Neuroscience

·April 19, 2024·5 min read

Eye Tests Predict Parkinson’s Progression

Optical coherence tomography, commonly used in eye exams, can monitor neurodegeneration in Parkinson's disease patients by measuring the thickness of the retina. This method has revealed that retinal degeneration often precedes cognitive and motor decline, offering a potential early indicator of disease progression.

This shows a researcher looking at a computer screen.

Featured Neurology Neuroscience

·April 17, 2024·5 min read

AI Revolutionizes Hunt for Parkinson’s Treatments

Researchers employed AI to fast-track the discovery of treatments for Parkinson's disease. They utilized machine learning techniques to screen millions of compounds and successfully identified five promising candidates that prevent the harmful clumping of alpha-synuclein, a key protein in Parkinson’s pathology.

Featured Neurology Neuroscience

·April 16, 2024·4 min read

Monoclonal Antibody Slows Rapid Motor Decline in Parkinson’s

Prasinezumab, a monoclonal antibody targeting alpha-synuclein aggregation, shows promise in slowing motor deterioration in rapidly progressing Parkinson's disease (PD), according to an exploratory analysis from the phase 2 PASADENA clinical trial. While there are currently no disease-modifying treatments for PD, prasinezumab offers a potential breakthrough by specifically binding to aggregated alpha-synuclein, a key driver of PD pathology.

Featured Neurology Neuroscience Psychology

·April 16, 2024·4 min read

Emotional Bodily Sensations Altered in Parkinson’s Patients

People with Parkinson’s disease experience altered bodily sensations related to basic emotions differently from healthy individuals. Utilizing electronic body maps, participants identified how emotions like anger, happiness, and sadness manifested physically, noting significant shifts in sensation locations, particularly with anger moving from the chest to the abdomen.

Featured Neurology Neuroscience

·April 15, 2024·7 min read

Brain Area Linked to Attention Control Identified

Deep brain stimulation (DBS) in the subthalamic nucleus, a treatment for Parkinson's disease, may influence more than just motor control. This treatment, which mitigates Parkinson's symptoms such as tremors, also appears to affect patients' ability to shift their attention between tasks.

Featured Neurology Neuroscience

·April 11, 2024·6 min read

Nose vs. Gut: Unraveling Parkinson’s Toxic Origins

A pivotal hypothesis paper challenges existing theories on Parkinson's disease origins, proposing environmental toxicants as key culprits. This study suggests that Parkinson's can start from the brain's smell center or the gut, influenced by inhaled or ingested toxins.

1 … 5 6 7 8 9 … 76

Parkinson’s disease

Blood Test Predicts Parkinson’s Years Before Symptoms

Vitamin B Deficiency in Gut Linked to Parkinson’s

Cancer Drug May Halt Parkinson’s Spread

Age-Linked Sympathetic Denervation Worsens PD Non-Motor Symptoms

Caffeine Intake Doesn’t Slow Parkinson’s Progression

Enhancing Neurogenesis for Parkinson’s Treatment

Eye Tests Predict Parkinson’s Progression

AI Revolutionizes Hunt for Parkinson’s Treatments

Monoclonal Antibody Slows Rapid Motor Decline in Parkinson’s

Emotional Bodily Sensations Altered in Parkinson’s Patients

Brain Area Linked to Attention Control Identified

Nose vs. Gut: Unraveling Parkinson’s Toxic Origins

Minibrains Reveal Personalized Paths for Rett Syndrome

50-Millisecond Brain Filter That Decodes Odors

Inhibitory Neurons Drive Rhythmic Movement

Somatic Evolution Revealed as a Primary Driver of Autoimmune Disease

Subscribe