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Parkinson’s disease

Featured Genetics Neurology Neuroscience

·July 29, 2024·5 min read

Rapid Stem Cell Model Advances Parkinson’s Research

Researchers have developed a model that quickly converts stem cells to brain cells with Parkinson’s disease (PD) protein structures, allowing for personalized study and treatment. This new approach can transform stem cells into brain cells within weeks, facilitating high-throughput genetic and drug screening. By mimicking diverse protein misfolding seen in PD patients, the model offers a practical tool for diagnostics and drug discovery. This advancement could lead to personalized therapies for Parkinson's and related neurodegenerative diseases.

Featured Neurology Neuroscience

·July 16, 2024·5 min read

AI Identifies Three Parkinson’s Subtypes

Researchers used machine learning to identify three subtypes of Parkinson’s disease based on progression speed. These subtypes, marked by distinct genetic drivers, could enhance diagnosis and treatment strategies.

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Featured Neurology Neuroscience Psychology

·June 25, 2024·3 min read

Anxiety Doubles Parkinson’s Risk

Researchers found that people over 50 with anxiety have twice the risk of developing Parkinson’s disease. Using UK primary care data from 2008-2018, the study compared 109,435 patients with anxiety to 878,256 without. Results showed increased Parkinson’s risk and identified additional risk factors like depression and sleep problems. This research suggests early detection and treatment for Parkinson’s might be possible by monitoring anxiety and related symptoms.

Featured Neurology Neuroscience

·June 18, 2024·6 min read

Blood Test Predicts Parkinson’s Years Before Symptoms

Researchers have developed an AI-powered blood test that can predict Parkinson's disease up to seven years before symptoms appear. The test analyzes eight blood biomarkers and has shown 100% accuracy in diagnosing the disease. This breakthrough offers the potential for early intervention and treatment before significant damage occurs in the brain.

Featured Genetics Neurology Neuroscience

·June 18, 2024·5 min read

Vitamin B Deficiency in Gut Linked to Parkinson’s

A new study reveals a link between gut bacteria and Parkinson's disease (PD). Researchers found a decrease in genes responsible for synthesizing essential B vitamins in PD patients, which may weaken the intestinal barrier and lead to inflammation in the brain. This finding suggests that B vitamin supplementation could be a potential therapeutic avenue for PD.

Brain Cancer Featured Neurology Neuroscience

·June 17, 2024·5 min read

Cancer Drug May Halt Parkinson’s Spread

Researchers discovered a novel therapeutic target for Parkinson's disease, the Aplp1 protein, which facilitates the spread of harmful alpha-synuclein proteins in the brain. Notably, an FDA-approved cancer drug targeting Lag3, a protein that interacts with Aplp1, has shown promise in blocking this spread in mouse models.

Featured Neurology Neuroscience

·May 30, 2024·5 min read

Age-Linked Sympathetic Denervation Worsens PD Non-Motor Symptoms

Researchers found that Parkinson’s disease (PD) patients with sympathetic denervation in major salivary glands and the heart exhibit more severe non-motor symptoms as they age. This research highlights the importance of age in PD progression and could enhance the understanding of the disease's pathophysiology.

Featured Neurology Neuroscience

·May 28, 2024·4 min read

Caffeine Intake Doesn’t Slow Parkinson’s Progression

A new study examined the impact of caffeine on brain dopamine function in Parkinson's patients, finding no benefits on disease progression. High caffeine consumption was linked to a greater decrease in dopamine transporter binding, likely due to a compensatory mechanism rather than neuron loss.

Featured Genetics Neurology Neuroscience

·April 30, 2024·4 min read

Enhancing Neurogenesis for Parkinson’s Treatment

Researchers have pioneered a method to enhance the generation of dopaminergic neurons, crucial for Parkinson’s disease treatment, by targeting specific receptors within the Wnt signaling pathway. Using synthetic antibodies, the team successfully directed stem cell differentiation in the midbrain to produce these key neurons, which are instrumental in brain health and depleted in Parkinson’s patients.

Featured Neurology Neuroscience Visual Neuroscience

·April 19, 2024·5 min read

Eye Tests Predict Parkinson’s Progression

Optical coherence tomography, commonly used in eye exams, can monitor neurodegeneration in Parkinson's disease patients by measuring the thickness of the retina. This method has revealed that retinal degeneration often precedes cognitive and motor decline, offering a potential early indicator of disease progression.

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Featured Neurology Neuroscience

·April 17, 2024·5 min read

AI Revolutionizes Hunt for Parkinson’s Treatments

Researchers employed AI to fast-track the discovery of treatments for Parkinson's disease. They utilized machine learning techniques to screen millions of compounds and successfully identified five promising candidates that prevent the harmful clumping of alpha-synuclein, a key protein in Parkinson’s pathology.

Featured Neurology Neuroscience

·April 16, 2024·4 min read

Monoclonal Antibody Slows Rapid Motor Decline in Parkinson’s

Prasinezumab, a monoclonal antibody targeting alpha-synuclein aggregation, shows promise in slowing motor deterioration in rapidly progressing Parkinson's disease (PD), according to an exploratory analysis from the phase 2 PASADENA clinical trial. While there are currently no disease-modifying treatments for PD, prasinezumab offers a potential breakthrough by specifically binding to aggregated alpha-synuclein, a key driver of PD pathology.

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Parkinson’s disease

Rapid Stem Cell Model Advances Parkinson’s Research

AI Identifies Three Parkinson’s Subtypes

Anxiety Doubles Parkinson’s Risk

Blood Test Predicts Parkinson’s Years Before Symptoms

Vitamin B Deficiency in Gut Linked to Parkinson’s

Cancer Drug May Halt Parkinson’s Spread

Age-Linked Sympathetic Denervation Worsens PD Non-Motor Symptoms

Caffeine Intake Doesn’t Slow Parkinson’s Progression

Enhancing Neurogenesis for Parkinson’s Treatment

Eye Tests Predict Parkinson’s Progression

AI Revolutionizes Hunt for Parkinson’s Treatments

Monoclonal Antibody Slows Rapid Motor Decline in Parkinson’s

New Drug Exposes Hidden Subtypes of Psychosis

New Study Uncovers the Structural Key to How Cells Ship Cargo

Meditation Retreat Sparks Rapid Brain & Immune System Changes

AI-Driven Brain Implant Brings “Two-Way” Artificial Vision Closer to Reality

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