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oligodendrocytes

·March 28, 2024·7 min read

Aging Brain Cells Have Prolonged Death Process

Mature oligodendrocytes, crucial for brain function and myelin production, have an unusually prolonged death process after damage, surviving up to 45 days post-trauma, a stark contrast to the rapid demise of their younger counterparts within 24 hours. This study illuminates a previously unknown pathway of cell longevity, suggesting a potential shift in strategies for treating aging-related damage and neurodegenerative diseases like multiple sclerosis.

Featured Neurology Neuroscience

·January 24, 2023·4 min read

How a Brain Molecule Could Halt Multiple Sclerosis

Injecting the brain molecule into mouse models of multiple sclerosis increased the number of oligodendrocytes. The findings suggest fractalkine may help to slow the progression, or potentially halt multiple sclerosis.

This shows oligodendrocyte precursor cells

Electrophysiology Featured Neuroscience

·November 28, 2022·6 min read

Scientists Capture Detailed Snapshots of Mouse Brain Cells Nibbling on Neurons

Oligodendrocyte precursor cells (OPCs) play a significant role in synaptic pruning, a new study reveals.

Featured Neuroscience

·May 6, 2022·2 min read

Oligodendrocytes Arise in the Human Brain Earlier in Development

Researchers discovered oligodendrocytes, myelin-producing cells within the central nervous system, become established in the brain during early fetal development.

This shows a person's finger zapping a brain with electricity

Featured Neurology Neuroscience

·March 12, 2022·4 min read

Brain Cell Insight Could Lead to New Treatments for Neurological-Based Diseases

Study reports oligodendrocytes in the brain are distinct from oligodendrocytes in the central nervous system due to their metabolic processes. The findings may shed new light on neurological and autoimmune dysfunction in multiple sclerosis and other neurodegenerative disorders.

Featured Genetics Neurology Neuroscience

·February 4, 2022·3 min read

New Genetic Clues for Multiple Sclerosis Risk

Oligodendrocytes may play a different role in the development and progression of multiple sclerosis than previously thought.

Autism Featured Genetics Neuroscience

·December 21, 2021·4 min read

Autism-Linked Gene, if Deleted, Results in Less Myelin

The deletion of the autism-associated Tbx1 gene results in slower cognitive processing and decreased myelin in mouse models.

Featured Neurology Neuroscience

·June 14, 2021·3 min read

A New Model of Alzheimer’s Progression

A new model of Alzheimer's progression highlights the link between glial cells, toxic protein buildup, and neurodegeneration.

Featured Neurology Neuroscience

·June 2, 2021·8 min read

How HIV Infection Shrinks the Brain’s White Matter

HIV infection prevents myelin-associated oligodendrocytes from maturing, this, in turn, hampers white matter production in the brain.

Featured Neurology Neuroscience

·March 9, 2021·5 min read

Myelin Loss Is a Major Factor in Age-Related Brain Deterioration

Cells that drive myelin repair become less efficient due to aging. Myelin loss results in cognitive decline and is central to a number of neurodegenerative diseases.

Featured Genetics Neurology Neuroscience

·May 19, 2020·2 min read

Animal study shows human brain cells repair damage in multiple sclerosis

Human iPSCs transplanted into animal models of multiple sclerosis help repair cell damage and restore function.

Featured Genetics Neurology Neuroscience

·April 27, 2020·3 min read

More evidence Parkinson’s disease may start in the gut

Enteric neurons appear to play a key role in the development of Parkinson's disease. The findings support the hypothesis and previous studies that the neurodegenerative disease may start in the gut before spreading to the brain. Researchers also found oligodendrocytes were affected during the early stages of Parkinson's, even before the loss of dopaminergic neurons.