Injecting the brain molecule into mouse models of multiple sclerosis increased the number of oligodendrocytes. The findings suggest fractalkine may help to slow the progression, or potentially halt multiple sclerosis.
Oligodendrocyte precursor cells (OPCs) play a significant role in synaptic pruning, a new study reveals.
Researchers discovered oligodendrocytes, myelin-producing cells within the central nervous system, become established in the brain during early fetal development.
Study reports oligodendrocytes in the brain are distinct from oligodendrocytes in the central nervous system due to their metabolic processes. The findings may shed new light on neurological and autoimmune dysfunction in multiple sclerosis and other neurodegenerative disorders.
Oligodendrocytes may play a different role in the development and progression of multiple sclerosis than previously thought.
The deletion of the autism-associated Tbx1 gene results in slower cognitive processing and decreased myelin in mouse models.
A new model of Alzheimer's progression highlights the link between glial cells, toxic protein buildup, and neurodegeneration.
HIV infection prevents myelin-associated oligodendrocytes from maturing, this, in turn, hampers white matter production in the brain.
Cells that drive myelin repair become less efficient due to aging. Myelin loss results in cognitive decline and is central to a number of neurodegenerative diseases.
Human iPSCs transplanted into animal models of multiple sclerosis help repair cell damage and restore function.
Enteric neurons appear to play a key role in the development of Parkinson's disease. The findings support the hypothesis and previous studies that the neurodegenerative disease may start in the gut before spreading to the brain. Researchers also found oligodendrocytes were affected during the early stages of Parkinson's, even before the loss of dopaminergic neurons.
Postmortem study reveals those with ASD have cellular abnormalities that impair the production of myelin.
