CYFIP1 plays a key role in the damaging effects of 15q11.2 deletion. When CYFIP1 is missing, myelin abnormalities occur. The findings shed light on how psychiatric disorders, such as schizophrenia and autism, may develop.
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Axon myelination is significantly disrupted in patients with Alzheimer's disease. Researchers also found brain cells of men and women vary significantly in how their genes respond to the neurodegenerative disease.
For the first time ever, stem cells from umbilical cords have been converted into other types of cells, which may...
A global knockout of the thrombin receptor PAR1 accelerates myelin development. The findings could help with the development of treatments for diseases associated with demyelination, like multiple sclerosis.
UCSF researchers reveal a common over the counter antihistamine appears to accelerate neural signaling and restore nervous system functioning for some multiple sclerosis patients.
Study reports oligodendrocytes in the brain are distinct from oligodendrocytes in the central nervous system due to their metabolic processes. The findings may shed new light on neurological and autoimmune dysfunction in multiple sclerosis and other neurodegenerative disorders.
Findings could help researchers develop new treatments for the most devastating forms of multiple sclerosis and other demyelinated diseases.
The death of myelin producing oligodendrocytes appears to trigger multiple sclerosis like symptoms in mice, a new study reports.
Researchers report oligodendrocytes may be critical to the remyelination process.