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neuroinflammation

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Featured Genetics Neuroscience Psychology

·April 1, 2022·5 min read

Genetically Determined Levels of Inflammation Linked to Neuropsychiatric Illness

Genes associated with inflammation were linked to reduced gray matter in brain areas associated with neuropsychiatric disorders. The findings shed new light on how neurodevelopmental psychiatric disorders such as schizophrenia and ASD may occur.

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Featured Neurology Neuroscience

·March 29, 2022·4 min read

Promising Alzheimer’s Drug May Also Improve Memory in Down Syndrome and Normal Aging

GM-CSF/sargramostim, a drug that improved memory in Alzheimer's patients during a phase II clinical trial, also appears to improve cognitive function in older adults and those with Down syndrome.

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Featured Neurology Neuroscience Open Neuroscience Articles

·March 21, 2022·3 min read

Intranasal Drug Halts Memory Decay in Experimental Alzheimer’s Model

Intranasal delivery of biologically active lipid messengers halts memory loss and neurodegeneration in mouse models of Alzheimer's disease.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 19, 2022·5 min read

New Strategy Reduces Brain Damage in PSP, Alzheimer’s, and Related Disorders in Mice

Alpha2-NKA, a protein that drives toxicity in astrocytes, was discovered in higher levels of brain samples from people who died of PSP, Alzheimer's and other tau-related neurodegenerative disorders. Treatment with an FDA-approved drug called digoxin may suppress the inflamed astrocytes and halt disease progression for those with tauopathy disorders.

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Featured Neurology Neuroscience

·March 18, 2022·3 min read

How Coronavirus Triggers Immune Response in Brain

Study reveals how COVID-19's spike protein has a similar effect on the brain's immune cells as it does throughout the rest of the body.

Featured Neurology Neuroscience

·March 13, 2022·5 min read

Even Mild COVID Can Cause Brain Shrinkage and Affect Mental Function

Even mild COVID-19 infection can lead to cognitive alterations and brain shrinkage, researchers report. The findings could help explain the brain changes that contribute to long-COVID.

Featured Neurology Neuroscience

·March 2, 2022·2 min read

Drug Candidate Reduced Brain Inflammation and Protected Against Cognitive Decline in Alzheimer’s Mouse Model

3,6’-dithiopomalidomide (DP), an anti-inflammatory drug candidate, protected mouse models of Alzheimer's disease against cognitive decline by reducing neuroinflammation.

Featured Neurology Neuroscience

·February 22, 2022·3 min read

Plant Product Shows Promise in Mouse Model of Parkinson’s Disease

Kushen, a dried root of a pea plant, may alleviate symptoms of neuroinflammation in Parkinson's disease when combined with an enzyme inhibitor.

Featured Neurology Neuroscience Open Neuroscience Articles

·February 17, 2022·4 min read

Bacteria in the Nose May Increase Risk of Alzheimer’s Disease

Chlamydia pneumoniae, a bacterium that is commonly present in the nose, can invade the brain via nerves in the nasal cavity. Once the bacterium is in the central nervous system, brain cells react within days, depositing Alzheimer's-associated amyloid-beta peptides.

Featured Neurology Neuroscience Open Neuroscience Articles

·January 27, 2022·3 min read

Could Long-Dead Bacteria Be the Culprit Behind Lingering Lyme Symptoms?

The remnants of the Lyme causing B. burgdorferi bacteria may be responsible for the neuroinflammation associated with long-term Lyme disease symptoms. Researchers say the remnants are more inflammatory than the live bacteria.

Featured Neurology Neuroscience

·January 12, 2022·5 min read

Inflammatory Markers Are Conspicuous During an Early Stage of Alzheimer’s

Proteins belonging to the TAM family receptors may be a new biomarker for Alzheimer's disease. The elevated inflammatory markers are conspicuous, even before the onset of dementia.