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neuroinflammation

·April 20, 2022·4 min read

When Severe Infection Causes Long-Term Mood Disorders

The activation of a neural circuit comprising of the central nucleus of the amygdala and the bed nucleus of the stria terminalis in the first hours following sepsis infection induced anxiety behaviors in mice two weeks after the infection cleared. The behaviors mimicked the PTSD symptoms patients experience following sepsis infection.

Featured Neuroscience Open Neuroscience Articles

·April 18, 2022·5 min read

Vaping Alters Inflammatory State of Brain, Heart, Lungs, and Colon

Daily vaping of pod-based e-cigarettes alters inflammatory states across multiple organs, including the brain. The effects vary depending upon the vape flavors and influence how the body responds to infections. Mint vapes, for example, leave people more sensitive to the effects of bacterial pneumonia than mango flavoring.

This shows the outline of a head and a brain

Featured Genetics Neuroscience Psychology

·April 1, 2022·5 min read

Genetically Determined Levels of Inflammation Linked to Neuropsychiatric Illness

Genes associated with inflammation were linked to reduced gray matter in brain areas associated with neuropsychiatric disorders. The findings shed new light on how neurodevelopmental psychiatric disorders such as schizophrenia and ASD may occur.

This shows the outline of two heads made up of tree branches

Featured Neurology Neuroscience

·March 29, 2022·4 min read

Promising Alzheimer’s Drug May Also Improve Memory in Down Syndrome and Normal Aging

GM-CSF/sargramostim, a drug that improved memory in Alzheimer's patients during a phase II clinical trial, also appears to improve cognitive function in older adults and those with Down syndrome.

This shows a model of a head and a brain

Featured Neurology Neuroscience Open Neuroscience Articles

·March 21, 2022·3 min read

Intranasal Drug Halts Memory Decay in Experimental Alzheimer’s Model

Intranasal delivery of biologically active lipid messengers halts memory loss and neurodegeneration in mouse models of Alzheimer's disease.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 19, 2022·5 min read

New Strategy Reduces Brain Damage in PSP, Alzheimer’s, and Related Disorders in Mice

Alpha2-NKA, a protein that drives toxicity in astrocytes, was discovered in higher levels of brain samples from people who died of PSP, Alzheimer's and other tau-related neurodegenerative disorders. Treatment with an FDA-approved drug called digoxin may suppress the inflamed astrocytes and halt disease progression for those with tauopathy disorders.

This shows a woman in a facemask surrounded by covid

Featured Neurology Neuroscience

·March 18, 2022·3 min read

How Coronavirus Triggers Immune Response in Brain

Study reveals how COVID-19's spike protein has a similar effect on the brain's immune cells as it does throughout the rest of the body.

Featured Neurology Neuroscience

·March 13, 2022·5 min read

Even Mild COVID Can Cause Brain Shrinkage and Affect Mental Function

Even mild COVID-19 infection can lead to cognitive alterations and brain shrinkage, researchers report. The findings could help explain the brain changes that contribute to long-COVID.

Featured Neurology Neuroscience

·March 2, 2022·2 min read

Drug Candidate Reduced Brain Inflammation and Protected Against Cognitive Decline in Alzheimer’s Mouse Model

3,6’-dithiopomalidomide (DP), an anti-inflammatory drug candidate, protected mouse models of Alzheimer's disease against cognitive decline by reducing neuroinflammation.

Featured Neurology Neuroscience

·February 22, 2022·3 min read

Plant Product Shows Promise in Mouse Model of Parkinson’s Disease

Kushen, a dried root of a pea plant, may alleviate symptoms of neuroinflammation in Parkinson's disease when combined with an enzyme inhibitor.

Featured Neurology Neuroscience Open Neuroscience Articles

·February 17, 2022·4 min read

Bacteria in the Nose May Increase Risk of Alzheimer’s Disease

Chlamydia pneumoniae, a bacterium that is commonly present in the nose, can invade the brain via nerves in the nasal cavity. Once the bacterium is in the central nervous system, brain cells react within days, depositing Alzheimer's-associated amyloid-beta peptides.

Featured Neurology Neuroscience Open Neuroscience Articles

·January 27, 2022·3 min read

Could Long-Dead Bacteria Be the Culprit Behind Lingering Lyme Symptoms?

The remnants of the Lyme causing B. burgdorferi bacteria may be responsible for the neuroinflammation associated with long-term Lyme disease symptoms. Researchers say the remnants are more inflammatory than the live bacteria.

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neuroinflammation

When Severe Infection Causes Long-Term Mood Disorders

Vaping Alters Inflammatory State of Brain, Heart, Lungs, and Colon

Genetically Determined Levels of Inflammation Linked to Neuropsychiatric Illness

Promising Alzheimer’s Drug May Also Improve Memory in Down Syndrome and Normal Aging

Intranasal Drug Halts Memory Decay in Experimental Alzheimer’s Model

New Strategy Reduces Brain Damage in PSP, Alzheimer’s, and Related Disorders in Mice

How Coronavirus Triggers Immune Response in Brain

Even Mild COVID Can Cause Brain Shrinkage and Affect Mental Function

Drug Candidate Reduced Brain Inflammation and Protected Against Cognitive Decline in Alzheimer’s Mouse Model

Plant Product Shows Promise in Mouse Model of Parkinson’s Disease

Bacteria in the Nose May Increase Risk of Alzheimer’s Disease

Could Long-Dead Bacteria Be the Culprit Behind Lingering Lyme Symptoms?

The Placenta May Decide Autism Vulnerability

Imaging Index Links Blood Flow to Cellular Architecture

Nighttime Light Exposure Linked to Sleep Loss in Schizophrenia

Eye-Blink Rate Predicts Cognitive Flexibility in Preschoolers

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