A new study in eLife provides evidence that our brains may drain waste via our lymphatic vessels. The vessels may act as a 'pipeline' between the brain and immune system. Researchers say the findings could alter the way we think about how the brain and immune system inter-relate.
A new study reports the locus coeruleus, an area of the brain essential for maintaining cognitive function, is vulnerable to toxins and infections. This brain area appears to be the first place affected by late onset Alzheimer's.
The 'shock and kill' therapeutic strategy for treating HIV could potentially cause harmful neuroinflammation, a new study reveals.
A 3D human tissue culture model demonstrated a possible causal relationship between Alzheimer's disease and herpes simplex virus 1 (HSV-1) infection. 40 Alzheimer's associated genes were over-expressed in the HSV-1 infected brain tissue, including genes associated with the production of amyloid-beta.
Reducing the expression of the protein TOM1 in mouse models of Alzheimer's disease increased the pathology, exacerbated cognitive problems, and raised levels of inflammation in the brain. Restoring TOM1 reversed the effects. Findings suggest a new therapeutic target for treating dementia.
According to a new mouse study, antibiotics that are strong enough to kill gut bacteria can also halt the growth of hippocampal neurons.