Latest

neuroinflammation

Featured Neuroscience Open Neuroscience Articles

·May 27, 2022·5 min read

Magnetic Resonance Imaging Shows Brain Inflammation in Vivo for the First Time

Neuroimaging technology allowed researchers to capture the activity of microglia and astrocytes in the brain. The researchers were able to quantify alterations in the morphology of different cell populations implicated in neuroinflammation.

Featured Neurology Neuroscience

·April 30, 2022·4 min read

A New Treatment Reduces Inflammation in Multiple Sclerosis Mice Models

Administering a lipid that mediates inflammation reduced chronic inflammation associated with multiple sclerosis in mouse models. Researchers found these mediator lipids are reduced in humans with multiple sclerosis.

This shows the outline of a head and a brain

Featured Neurology Neuroscience

·April 27, 2022·6 min read

How Effects on the Brain Can Produce Long COVID

Immune system mediated injury rather than the virus entering and killing brain cells may explain why people experience long-term consequences associated with COVID-19 infection.

This shows tissue macrophages in a mouse brain

Featured Genetics Neuroscience

·April 22, 2022·4 min read

New Discoveries About the Origin of the Brain’s Immune System

New findings reveal phagocytes do not fully mature until after birth, contradicting previous assumptions that they mature during embryonic development.

Featured Genetics Neurology Neuroscience

·April 20, 2022·5 min read

Single-Cell DNA Sequencing Offers a New Angle on the Causes of Alzheimer’s Disease

An abundance of newly acquired mutations in the mutations that occur at an accelerated speed is a telling pattern of Alzheimer's disease, researchers report.

Featured Neuroscience Psychology

·April 20, 2022·4 min read

When Severe Infection Causes Long-Term Mood Disorders

The activation of a neural circuit comprising of the central nucleus of the amygdala and the bed nucleus of the stria terminalis in the first hours following sepsis infection induced anxiety behaviors in mice two weeks after the infection cleared. The behaviors mimicked the PTSD symptoms patients experience following sepsis infection.

Featured Neuroscience Open Neuroscience Articles

·April 18, 2022·5 min read

Vaping Alters Inflammatory State of Brain, Heart, Lungs, and Colon

Daily vaping of pod-based e-cigarettes alters inflammatory states across multiple organs, including the brain. The effects vary depending upon the vape flavors and influence how the body responds to infections. Mint vapes, for example, leave people more sensitive to the effects of bacterial pneumonia than mango flavoring.

Featured Genetics Neuroscience Psychology

·April 1, 2022·5 min read

Genetically Determined Levels of Inflammation Linked to Neuropsychiatric Illness

Genes associated with inflammation were linked to reduced gray matter in brain areas associated with neuropsychiatric disorders. The findings shed new light on how neurodevelopmental psychiatric disorders such as schizophrenia and ASD may occur.

This shows the outline of two heads made up of tree branches

Featured Neurology Neuroscience

·March 29, 2022·4 min read

Promising Alzheimer’s Drug May Also Improve Memory in Down Syndrome and Normal Aging

GM-CSF/sargramostim, a drug that improved memory in Alzheimer's patients during a phase II clinical trial, also appears to improve cognitive function in older adults and those with Down syndrome.

This shows a model of a head and a brain

Featured Neurology Neuroscience Open Neuroscience Articles

·March 21, 2022·3 min read

Intranasal Drug Halts Memory Decay in Experimental Alzheimer’s Model

Intranasal delivery of biologically active lipid messengers halts memory loss and neurodegeneration in mouse models of Alzheimer's disease.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 19, 2022·5 min read

New Strategy Reduces Brain Damage in PSP, Alzheimer’s, and Related Disorders in Mice

Alpha2-NKA, a protein that drives toxicity in astrocytes, was discovered in higher levels of brain samples from people who died of PSP, Alzheimer's and other tau-related neurodegenerative disorders. Treatment with an FDA-approved drug called digoxin may suppress the inflamed astrocytes and halt disease progression for those with tauopathy disorders.