neurodegenerative diseases

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neurodegenerative diseases

·May 20, 2020·4 min read

Link between diesel exhaust and risk of Parkinson’s discovered

Researchers have uncovered the process by which air pollution can damage brain cells, leading to an increased risk of Parkinson's disease. Chemicals found in diesel fuel reduced autophagic flux, which is a major pathway implicated in neurodegeneration.

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·May 19, 2020·2 min read

Animal study shows human brain cells repair damage in multiple sclerosis

Human iPSCs transplanted into animal models of multiple sclerosis help repair cell damage and restore function.

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·May 16, 2020·4 min read

Certain Memory Complaints Predict Future Dementia

Subjective cognitive complaints may be the earliest detectable stages of preclinical dementia.

Featured Neurology Neuroscience

·May 15, 2020·4 min read

Gut microbiome influences ALS outcomes

Study reveals a new gut-brain connection in amyotrophic lateral sclerosis (ALS). The gut microbiome could influence the severity of the neurodegenerative disease. Altering the bacteria in the gut may prevent or improve symptoms of ALS.

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·May 14, 2020·4 min read

Retinal texture could provide early biomarker of Alzheimer’s disease

The topmost layer of neurons in the retina of mouse models of Alzheimer's disease exhibits textural changes. The findings could be a new biomarker for Alzheimer's disease.

Featured Neurology Neuroscience

·May 11, 2020·3 min read

Resilience to ALS due to synaptic safety mechanism

Study reveals a self-corrective mechanism within synapses that is activated by neurodegeneration and slows disease progression in animal models of ALS.

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·May 5, 2020·4 min read

New evidence that higher caffeine and urate levels are protective against Parkinson’s

Caffeine and urate have been associated with a reduced risk of idiopathic Parkinson's disease. Researchers noted a lower caffeine intake in idiopathic Parkinson's patients. Increasing caffeine consumption was linked to decreased odds of being diagnosed with Parkinson's. Lower levels of blood urate were also associated with an increased risk of Parkinson's disease.

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·May 5, 2020·6 min read

Flavonoid-rich berries, fruits and tea may have a protective benefit against Alzheimer’s

Consuming a flavonoid-rich diet could help combat the development and progression of Alzheimer's disease for those with risk factors. Low intake of specific flavonoids, especially anthocyanins, which are found in blueberries and strawberries, was associated with a four-fold risk of developing Alzheimer's.

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·May 4, 2020·4 min read

Artificial intelligence algorithm can accurately predict risk and diagnose Alzheimer’s disease

Combining brain imaging data with a new machine learning algorithm, researchers can accurately predict the risk and determine a diagnosis for Alzheimer's disease.

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·April 30, 2020·3 min read

Researchers unravel protein mystery of three brain diseases

Researchers have identified two different shapes of alpha-synuclein associated with multiple systems atrophy (MSA) and Lewy body dementia. The structure of the protein is helical in MSA, causing the symptoms to occur more quickly and aggressively. In Lewy body dementia, the protein takes on a cylindrical form.

Featured Genetics Neurology Neuroscience

·April 29, 2020·4 min read

APOE4 triggers early breakdowns in the blood-brain barrier

APOE4, a gene implicated as a risk factor for Alzheimer's disease, triggers leaks in the blood-brain barrier. The damage to capillaries APOE4 causes correlates with increased levels of cyclophilin, a protein that causes the inflammation that is a signature of early Alzheimer's.

Featured Genetics Neurology Neuroscience

·April 27, 2020·3 min read

More evidence Parkinson’s disease may start in the gut

Enteric neurons appear to play a key role in the development of Parkinson's disease. The findings support the hypothesis and previous studies that the neurodegenerative disease may start in the gut before spreading to the brain. Researchers also found oligodendrocytes were affected during the early stages of Parkinson's, even before the loss of dopaminergic neurons.

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