FeaturedNeuroscienceOpen Neuroscience Articles·November 6, 2022·5 min readNine Out of Ten Want to Know Their Brain Disease Risk91% of people say they would definitely like to take a simple test to analyze their risks of developing neurological disorders if they were available.Read More
FeaturedNeurologyNeuroscience·August 15, 2022·6 min readNew Role for Blood-Brain Barrier in Neuron Function and DamageThe signals that originate in the cells of the blood-brain barrier also play a direct role in controlling what happens to the neurons the barrier is protecting.Read More
FeaturedGeneticsNeurologyNeuroscience·November 29, 2021·5 min readWhy Some People Experience Early Onset Neurodegenerative DiseasesA new study sheds light on the genetic causes of a range of neurodegenerative disorders, including ALS, Parkinson's disease, and Huntington's disease, and determines factors that impact the age of onset as well as disease severity.Read More
FeaturedNeurologyNeuroscience·October 5, 2021·4 min readStudy Detects Origins of Huntington’s Disease in Two-Week-Old Human EmbryosSynthesizing a human embryo from stem cells and using gene editing to insert the Huntingtin gene, researchers found the mutation affected the size of germ layers compared to the control embryos. Findings suggest Huntington's disease may be a neurodevelopmental disorder that presents as a neurodegenerative disease laterRead More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·September 13, 2021·5 min readStudy Finds Evidence of Possible Link Between Herpes Simplex and Neurogenerative DiseasesResearchers discovered mutations of the OPTN gene resulted in increased herpesvirus 1 growth in the brains of mice, leading to the death of local neurons. This resulted in accelerated neurodegeneration. OPTN deficiency was also associated with impairments in immune response. While these findings are specific to the HSV-1 virus, researchers believe the findings may apply to up to eight herpesvirus infections.Read More
FeaturedNeurologyNeuroscience·September 8, 2021·2 min readNew Information on the Early Stages of Dementia With Lewy BodiesNew findings reinforce the idea that dementia with Lewy bodies can be pathologically classified as two different and distinct disease types.Read More
ElectrophysiologyFeaturedNeuroscienceOpen Neuroscience Articles·August 19, 2021·5 min readFlawed Quality Control in the BrainA new mouse line makes the state of protein balance visible in the mammalian brain for the first time, allowing researchers to investigate disorders associated with protein misfolding.Read More
FeaturedNeurologyNeuroscience·August 14, 2021·3 min readA New Way to Study Neurodegenerative DiseasesResearchers have developed a new technique to quantify protein droplets associated with a range of neurodegenerative diseases, including Alzheimer's, Parkinson's, and ALS.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·August 6, 2021·5 min readKey Hallmark of ALS ReversedResearchers reveal how proteins accumulate in the incorrect parts of brain cells in ALS, and demonstrate how it may be possible to reverse the accumulation.Read More
FeaturedNeurologyNeuroscience·July 19, 2021·3 min readChemists Found an Effective Remedy for “Aged” Brain DiseasesNewly synthesized compounds can halt the degradation of neurons in a range of neurodegenerative diseases, including Alzheimer's and Parkinson's disease, researchers say.Read More
FeaturedNeurologyNeuroscience·July 15, 2021·4 min readAutophagy May Be the Key to Finding Treatments for Early Huntington’s DiseaseDisruption of autophagy may be at the root of the cognitive deficits experienced by those with Huntington's disease.Read More
FeaturedNeuroscienceOpen Neuroscience Articles·June 27, 2021·3 min readDifferences in Human, Mouse Brain Cells Have Important Implications for Disease ResearchA new study reveals humans and mice have significant differences in how oxidative stress and inflammation trigger immune response genes in astrocytes. Researchers suggest lab models of neurodegeneration should incorporate specially engineered mouse models with lower resistance to oxidative stress, rendering them more human-like.Read More