mPFC

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mPFC

Coping strategies, a matter of neuron

Researchers uncover a key role of medial prefrontal cortex corticotropin-releasing factor interneurons for bidirectionally controlling motivated behavioral styles under stress. The findings could help in the development of new treatments for PTSD. Read More

This shows the mPFC and striatum highligted on a brain scan

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Rich rewards: ADHD medication’s effect on the brain

Methylphenidate may boost norepinephrine levels in the prefrontal cortex, which in turn regulates dopaminergic neurons firing in the striatum, when a reward is delivered. The study sheds new light on how medications for ADHD affect the reward system in the brain. Read More

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How to tell if a brain is awake

Study finds EEG features may not always be accurate in being able to capture the level of consciousness in patients under anesthesia. Read More

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Deepening our understanding of selfish behavior

Study identifies distinct neural processes that occur when we make decisions for the benefit of ourselves and of others. Read More

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How our dreams prepare us to face our fears

Study identified the neural correlates of fear during dreaming and reports similar areas are activated when experiencing fear during wakeful states. Read More

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What leads to compulsive alcohol use?

A network linking the medial prefrontal cortex and brainstem plays a critical role in the development of compulsive drinking disorder and is a driver for its expression. Read More

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What your friends’ brains look like when they think of you

To accurately perceive another person, your neural representation of that person has to match the pattern in the persons' brain when they think about themselves. Read More

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Stressed to the max? Deep sleep can rewire the anxious brain

Deep sleep restores the medial prefrontal cortex mechanisms that restore emotion. This lowers emotional and physiological reactivity, preventing the escalation of stress and anxiety. Read More

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How our brains remember things depends upon how we learn them

Neural pathways for learning differ depending on how each person has learned a new skill. Read More

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How emotion affects action

Researchers have identified a comprehensive circuit mechanism that governs how emotional states can influence movement through connections in the basal ganglia. The mechanism represents a way in which emotional states relate to changes in action control in depression, anxiety, and OCD. Read More

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Receptor protein in brain promotes resilience to stress

S1PR3, a receptor found on the surface of brain cells, may play a key role in stress resilience. Veterans with severe PTSD symptoms had lower levels of the S1PR3 protein in their blood than peers without the disorder. Read More

This shows a skateboarder pulling some moves

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Adolescents’ fun seeking predicts both risk taking and prosocial behavior

A positive correlation has been identified between prosocial and rebellious behaviors in teens. The more risk taking behaviors a teen exhibited, the more likely they were to act prosocially. The findings suggest the same developmental processes are at work for both types of behaviors. Also noted was faster brain development in the medial prefrontal cortex predicted a decrease in rebellious behavior. Read More

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