Researchers reveal the role the prefrontal cortex plays in emotional processing and emotional suppression.
Researchers explore the effect psychedelics have on the brain and how they are effective at treating depression.
Study reveals blunted activity in the medial prefrontal cortex was associated with aggressive behaviors by abusive partners in relationships.
Novel experiences dampen previous memory representations in the hippocampus and prefrontal cortex, facilitating flexible strategy encoding in mice.
Neurons in the medial prefrontal cortex respond more to loss than to gain. Avoidance of risk-taking is affected by an area of the hippocampus that is associated with memory and anxiety. The findings suggest a close relationship between memory processing and decision making when risk is present, especially in stressful situations. The fresh insights might help guide new psychiatric therapies for disorders marked by excessive avoidance, such as anxiety, and depression, and also mania and addiction, where excessive risk-taking is a common feature.
Aging may alter neural processes for remembering continuous real-world experiences and segmenting memories.
Males with autism have atypically enhanced excitation in the medial prefrontal cortex (mPFC). This area of the brain is associated with social cognition and self-reflection. Autistic women showed a more intact mPFC response, which was associated with a better ability to camouflage social difficulties in real-world settings.
In the medial prefrontal cortex, loneliness is associated with a reduced representational similarity between the self and others. Feeling socially disconnected may be mirrored by a self-representation of being a "loner."