Neural patterns of activity in the medial prefrontal cortex associated with the intention to drink alcohol are influenced by the genetic risk for alcohol use disorder.
Neurons in the medial prefrontal cortex respond more to loss than to gain. Avoidance of risk-taking is affected by an area of the hippocampus that is associated with memory and anxiety. The findings suggest a close relationship between memory processing and decision making when risk is present, especially in stressful situations. The fresh insights might help guide new psychiatric therapies for disorders marked by excessive avoidance, such as anxiety, and depression, and also mania and addiction, where excessive risk-taking is a common feature.
Researchers identified specific neurons in the medial prefrontal cortex, called self monitoring error neurons, that fire immediately after people make a mistake.
Researchers uncover a key role of medial prefrontal cortex corticotropin-releasing factor interneurons for bidirectionally controlling motivated behavioral styles under stress. The findings could help in the development of new treatments for PTSD.
In a study exploring the neural correlates of the fight or flight response, people who choose to flee perceive a greater threat, leading them to behaviorally and mentally disengage from a situation, researchers report.
Findings suggest brain networks associated with impulse control could be weakened in people with gambling addiction.
Disruptions in an inhibitory brain circuit between the thalamus and prefrontal cortex may underlie cognitive disorders such as schizophrenia.
Study links common steroid used to prevent premature birth to impaired cognitive function in offspring.