FeaturedGeneticsNeuroscience·April 22, 2022·4 min readNew Discoveries About the Origin of the Brain’s Immune SystemNew findings reveal phagocytes do not fully mature until after birth, contradicting previous assumptions that they mature during embryonic development.Read More
FeaturedGeneticsNeurologyNeuroscience·April 20, 2022·5 min readSingle-Cell DNA Sequencing Offers a New Angle on the Causes of Alzheimer’s DiseaseAn abundance of newly acquired mutations in the mutations that occur at an accelerated speed is a telling pattern of Alzheimer's disease, researchers report.Read More
FeaturedNeuroscienceOpen Neuroscience Articles·April 19, 2022·3 min readWhen Neurons Behave Like a Double-Edged SwordResearchers report the intrinsic excitability of neurons in response to immune cell reaction to bacteria depends on the different neuron subtypes in rats.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·April 14, 2022·5 min readKey Signaling Pathway in Immune Cells Could Be New Alzheimer’s TargetTau-tangles trigger the inflammatory activation of microglia via the NF-κB pathway. Inhibiting the microglia NF-κB signaling pulled the immune cells out of their inflammatory state and reversed learning and memory problems in tau-based Alzheimer's mouse models.Read More
FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology·April 8, 2022·4 min readDepressive Disorders Can Lead to Changes in Immune CellsResearchers identified a link between major depressive disorder and mechanical alterations in blood cells.Read More
FeaturedNeurosciencePsychology·March 29, 2022·3 min readStudy Links Early Life Adversity, Microglia Dysfunction, to Aberrant Adult Stress Responses, Mental IllnessMicroglia dysfunction in those who experienced early life adversity prompts an aberrant stress response during adulthood that may be linked to mental illness.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·March 23, 2022·4 min readHow TREM2 Gene Mutation in Brain Microglia Immune Cells Can Increase Alzheimer’s RiskA molecular process caused by the TREM2 gene mutation in the brain's microglia increases the risk of Alzheimer's disease, a new study reports.Read More
FeaturedNeurologyNeuroscience·March 23, 2022·3 min readIntake of FDA-Approved Drug Modulates Disease Progression in Alzheimer’s ModelNiaspan, an FDA-approved drug, limits disease progression in lab models of Alzheimer's disease.Read More
FeaturedNeuroscience·March 7, 2022·2 min readUncovering How Immune Cells Nurture Brain ConnectionsA new study in mice finds microglia help neurons grow synapses critical for cognitive function.Read More
FeaturedNeuroscience·February 2, 2022·5 min readMechanism Behind Loss of Smell With COVID-19 RevealedInfection with the SARS_CoV-2 virus causes dials down the action of olfactory receptors, resulting in smell loss associated with COVID-19.Read More
FeaturedGeneticsNeurologyNeuroscience·January 9, 2022·3 min readResearch Clears up How Brain ‘Cleaners’ Fail in ALSFindings point to microglial TREM2 as a potential target for the treatment of ALS.Read More
FeaturedGeneticsNeuroscience·December 30, 2021·3 min readMicroglial Methylation Landscape in Human BrainMicroglia showed DNA methylation profiles that were distinct from other cells in the central nervous system.Read More
