FeaturedNeurologyNeurosciencePain·January 30, 2023·5 min readCalcium Channels Regulate Neuroinflammation and Neuropathic PainThe Orai1 class of calcium channels regulates sex differences in the functioning of immune cells associated with neuroinflammation and neuropathic pain.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·January 25, 2023·4 min readDrug That Targets Tauopathies in Mice Reveals Sex Differences in ResponseExposure to drugs that target tauopathies extended survival, reduced neurodegenerative biomarkers, and functionally reduced aberrant behaviors in female mice, but not in males.Read More
FeaturedNeuroscienceOpen Neuroscience Articles·January 17, 2023·3 min readHigh Fat Diet Activates Early Inflammation in Mouse Brains, Supports Link to Neurological DiseaseHigh-fat diets promote early inflammatory responses in the brain via an immune pathway associated with diabetes and neurodegenerative diseases. The findings suggest a link between metabolic dysfunction and cognitive impairment.Read More
FeaturedNeuroscience·January 6, 2023·5 min readNewly Discovered Anatomy Shields and Monitors BrainResearchers have discovered a previously unidentified component of brain anatomy that acts as both a protective barrier and a platform by which immune cells monitor the brain for signs of inflammation and infection.Read More
FeaturedGeneticsNeurologyNeuroscience·January 5, 2023·3 min readAlzheimer’s Disease Researchers Study Gene Associated With the Brain’s Immune CellsReduction of the INPP5D gene variant found in the brain's microglia could help to diminish the risk of late-onset Alzheimer's disease.Read More
FeaturedNeurologyNeuroscienceNeuroscience Videos·December 10, 2022·6 min readHarnessing the Brain’s Immune Cells to Stave off Alzheimer’s and Other Neurodegenerative DiseasesResearchers have identified a protein that could be leveraged to help microglia in the brain stave off Alzheimer's and other neurodegenerative diseases.Read More
FeaturedNeuroscience·November 29, 2022·3 min readKey Factors Identified for Regeneration of Brain TissueResearchers have identified two proteins that prevent the formation of scars in the brain and help promote the regeneration of new neural tissue.Read More
FeaturedNeurologyNeuroscience·November 29, 2022·3 min readThe Brain’s Immune Cells Can Be Triggered to Slow Down Alzheimer’s DiseaseActivating TREM2 on microglia in the brains of those with Alzheimer's could help slow down the progression of the neurodegenerative disease.Read More
FeaturedNeurologyNeuroscience·November 3, 2022·4 min readThe Brain’s Immune Cell Response in Alzheimer’s DiseaseDeletion of the neurodegenerative disease associated microglial gene CX3CR1 aggravated the disease state and increased the accumulation of plaques in the brains of mouse models of Alzheimer's disease. Deficiencies of the gene also impaired the movement of microglia toward the plaques.Read More
FeaturedNeurologyNeuroscience·October 19, 2022·4 min readCOVID-19 Linked to Excessive Destruction of Connections Between Nerve CellsCOVID-19 infection causes microglia to excessively engulf synaptic structures and the upregulation of factors involved in phagocytosis.Read More
FeaturedGeneticsNeuroscience·September 27, 2022·4 min readEnemy Turned Ally: Ancient Viral Genes Protect the Brain Against New InfectionsTwo mouse genes that were left behind by viral infections millions of years ago have evolved to help defend the brain against new infections.Read More
FeaturedGeneticsNeuroscience·August 25, 2022·3 min readWhat Makes the Human Brain Different?Researchers have identified human-specific cell types in the prefrontal cortex. These unique cells may explain why humans are more susceptible to neuropsychiatric diseases than other primate species.Read More
