FeaturedNeurologyNeuroscience·August 4, 2022·6 min readHow Microglia Contribute to Alzheimer’s DiseaseMicroglia that express the Alzheimer's associated APOE4 genetic variant are unable to effectively metabolize lipids. This causes lipids to build up, promoting inflammation and preventing effective neurotransmission.Read More
FeaturedNeurosciencePsychology·June 29, 2022·5 min readResearch Sheds Light on Mechanism by Which Long-Term Anti-Anxiety Drug Use Affects the BrainStudy reveals a possible mechanism by which anxiolytic medications act on the brain, leading to cognitive impairment.Read More
FeaturedNeurologyNeuroscience·June 21, 2022·4 min readProtein Changes in Cerebrospinal Fluid Indicate Inflammatory Processes in the BrainStudy identifies a group of proteins in the cerebrospinal fluid that could serve as biomarkers for inflammation in the brain.Read More
FeaturedNeuroscienceOpen Neuroscience Articles·May 27, 2022·5 min readMagnetic Resonance Imaging Shows Brain Inflammation in Vivo for the First TimeNeuroimaging technology allowed researchers to capture the activity of microglia and astrocytes in the brain. The researchers were able to quantify alterations in the morphology of different cell populations implicated in neuroinflammation.Read More
FeaturedNeurologyNeuroscience·May 27, 2022·5 min readSugar-Studded Protein Linked to Alzheimer’s DiseaseGlycan, a special sugar protein, appears to play a significant role in the development of Alzheimer's disease.Read More
AutismFeaturedGeneticsNeuroscienceOpen Neuroscience Articles·May 2, 2022·4 min readDoes Autism Begin in the Womb?Researchers found idiopathic autism occurs as the result of epigenetic abnormalities in hematopoietic cells during fetal development, leading to immune dysregulation in the brain and gut.Read More
FeaturedGeneticsNeuroscience·April 22, 2022·4 min readNew Discoveries About the Origin of the Brain’s Immune SystemNew findings reveal phagocytes do not fully mature until after birth, contradicting previous assumptions that they mature during embryonic development.Read More
FeaturedGeneticsNeurologyNeuroscience·April 20, 2022·5 min readSingle-Cell DNA Sequencing Offers a New Angle on the Causes of Alzheimer’s DiseaseAn abundance of newly acquired mutations in the mutations that occur at an accelerated speed is a telling pattern of Alzheimer's disease, researchers report.Read More
FeaturedNeuroscienceOpen Neuroscience Articles·April 19, 2022·3 min readWhen Neurons Behave Like a Double-Edged SwordResearchers report the intrinsic excitability of neurons in response to immune cell reaction to bacteria depends on the different neuron subtypes in rats.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·April 14, 2022·5 min readKey Signaling Pathway in Immune Cells Could Be New Alzheimer’s TargetTau-tangles trigger the inflammatory activation of microglia via the NF-κB pathway. Inhibiting the microglia NF-κB signaling pulled the immune cells out of their inflammatory state and reversed learning and memory problems in tau-based Alzheimer's mouse models.Read More
FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology·April 8, 2022·4 min readDepressive Disorders Can Lead to Changes in Immune CellsResearchers identified a link between major depressive disorder and mechanical alterations in blood cells.Read More
FeaturedNeurosciencePsychology·March 29, 2022·3 min readStudy Links Early Life Adversity, Microglia Dysfunction, to Aberrant Adult Stress Responses, Mental IllnessMicroglia dysfunction in those who experienced early life adversity prompts an aberrant stress response during adulthood that may be linked to mental illness.Read More
