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microglia

This shows the chemical structures of the four different molecules

·July 14, 2021·4 min read

Compound Derived From Turmeric Essential Oil Has Neuroprotective Properties

Aromatic turmerone, a compound derived from turmeric essential oil, and its derivatives directly affect dopamine neurons to generate neuroprotective properties in tissue culture models of Parkinson's disease.

Featured Genetics Neurology Neuroscience

·July 8, 2021·4 min read

ALS: Study Shows Role of Brain’s Immune Cells

Hyperactive microglia immune cells may play a significant role in the development of ALS, researchers report.

Featured Neuroscience Psychology

·June 14, 2021·4 min read

Inflammatory Processes Are Altered in the Brains of People With Opioid Use Disorder

Neuroinflammation may be a key player in the pathological brain changes produced as a result of chronic opioid use. Microglia is likely responsible for the majority of the changes.

Featured Neurology Neuroscience

·June 14, 2021·3 min read

A New Model of Alzheimer’s Progression

A new model of Alzheimer's progression highlights the link between glial cells, toxic protein buildup, and neurodegeneration.

Featured Neurology Neuroscience Open Neuroscience Articles

·June 8, 2021·4 min read

Immune Cell Behavior That Plays a Key Role in Alzheimer’s Disease Discovered

Sustained microglia activation leads to the cells becoming senescent. This leads to an accelerated accumulation of amyloid in the brain, influencing the early stages of Alzheimer's development.

Featured Neurology Neuroscience

·June 3, 2021·2 min read

Secondary Infections Inflame the Brain, Worsening Cognition in Alzheimer’s Disease

Secondary infections and novel inflammatory events, even ones that occur external to the brain, amplify the brain's immune response and detrimentally impact cognition in mouse models of Alzheimer's disease.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·May 21, 2021·4 min read

Gene Signature for Plaque-Eating Microglia in Alzheimer’s Disease Discovered

Study identifies gene expression signatures that underlie microglia associated with amyloid plaque phagocytosis.

Featured Neurology Neuroscience

·May 16, 2021·4 min read

Anesthetic May Affect Tau Spread in the Brain to Promote Alzheimer’s Disease Pathology

Sevoflurane, an anesthetic, causes tau to leave neurons and enter microglia. This stimulates the production of interleukin-6, leading to inflammation and cognitive impairment.

This shows AB plaques surrounded by microglia

Featured Genetics Neurology Neuroscience

·April 16, 2021·5 min read

Some Alzheimer’s Plaques May Be Protective, Not Destructive

Microglia creates dense-core plaques which help to clear away more wispy plaques from neurons, preventing cell death. Findings suggest the dense-core plaques play a defensive role in protecting the brain from the ravages of neurodegenerative diseases, such as Alzheimer's.