FeaturedGeneticsNeurologyNeuroscience·December 30, 2020·4 min readMutations Associated With Early Onset Dementia DiscoveredDisruptions in circulating white blood cells may be a key driver in ALSP, a rare form of early-onset dementia.Read More
FeaturedNeurosciencePsychology·December 28, 2020·7 min readMaternal Immune Activation Induces Sustained Changes in Fetal Microglia MotilityChanges in fetal microglia caused as a result of maternal inflammation could contribute to the development of schizophrenia, autism, and other psychiatric or developmental disorders.Read More
FeaturedNeuroscience·December 28, 2020·4 min readAstrocytes Eat Connections to Maintain Plasticity in Adult BrainsAstrocytes, not microglia, are responsible for constantly eliminating unnecessary and excessive adult synaptic connections in response to brain activity.Read More
FeaturedNeurologyNeuroscience·December 21, 2020·5 min readWhy Some Multiple Sclerosis Patients Experience SeizuresStudy identifies a pathway involving astrocytes that help explain why some with multiple sclerosis experience seizures.Read More
FeaturedGeneticsNeurologyNeuroscience·December 16, 2020·5 min readProtein Involved in Removing Alzheimer’s Buildup Linked to Circadian RhythmYKL-40 may be a key player in circadian rhythm disruptions associated with Alzheimer's disease.Read More
FeaturedGeneticsNeuroscience·December 14, 2020·5 min readAn Unexpected Role for the Brain’s Immune CellsMicroglia cells continuously survey the brain to help prevent sporadic seizures.Read More
FeaturedNeurologyNeuroscience·October 16, 2020·3 min readStudy Explains the Process That Exacerbates Multiple SclerosisRecovery from multiple sclerosis-like symptoms in mice depends upon the ability for microglia to break down the remains of damaged cells.Read More
FeaturedNeuroscience·September 30, 2020·4 min readNovel Role of Microglia as Modulators of Neurons in the Brain Is DiscoveredResearchers have identified a bio-chemical circuit that supports neuron-microglia communication. When neurons are active, they release ATP. Microglia sense extracellular ATP and the compound draws the immune cell toward the neuron.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·September 25, 2020·5 min readA Genetic Variant That Protects Against Alzheimer’s Promotes Immune Cell FunctionsPLCG2-P522R, a genetic variant that protects against Alzheimer's disease, enhances key functions of immune cells.Read More
FeaturedNeuroscienceOpen Neuroscience Articles·September 15, 2020·4 min readKey Role of Immune Cells in Brain Infection IdentifiedStudy identifies a specific type of immune cell that induces inflammation in herpes simplex virus (HSV) encephalitis.Read More
FeaturedGeneticsNeuroscience·September 14, 2020·4 min readImmune Cells Sculpt Circuits in the BrainMicroglia, immune cells that protect the brain from infection and inflammation, also appear to play a critical role in sculpting circuits in the developing brain.Read More
FeaturedNeuroscienceOpen Neuroscience Articles·August 11, 2020·5 min readScientists Replace Malfunctioning ‘Vacuum Cleaner’ Cells Linked to Neurological DisordersResearchers have devised techniques that allowed them to successfully replace dysfunctional microglia.Read More