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          macrophages

          This shows macrophages.
          FeaturedNeuroscience
          ·July 16, 2026·17 min read

          Macrophage Receptor Blockade Reverses Multi-Organ Aging

          Age-related multi-organ decline is driven by an EP2-receptor-mediated failure of tissue-resident macrophages to clear senescent neutrophils.
          Read More
          Nerves (in green) within a melanoma tumor.
          Brain CancerFeaturedGeneticsNeuroscience
          ·April 29, 2026·8 min read

          Sympathetic Nerves Found to Slow Melanoma Growth

          A new study reveals a "brake" on cancer growth: sympathetic nerves inhibit melanoma by reducing pro-tumor macrophages.
          Read More
          This is an AI rendition of macrophages in muscle tissue.
          FeaturedNeuroscience
          ·December 4, 2024·5 min read

          Immune Cells Modulate Movement and Energy

          Macrophages, immune cells typically known for fighting infections, have been discovered to play a vital role in controlling movement and linking neural activity with metabolic demands. Located in muscle spindles, these cells modulate neural activity using glutamate signaling, fine-tune muscle contractions, and optimize energy use during physical activity.
          Read More
          This shows a macrophage.
          FeaturedNeurologyNeuroscience
          ·June 12, 2023·8 min read

          Cellular Custodians: ‘Big Eater’ Macrophages May Hold Key to Autoimmune Disease Treatment

          The mysterious workings of tingible body macrophages (TBMs) have been substantially demystified. These TBMs, a subtype of macrophages within our lymph nodes, were found to devour antibody-producing B cells, a function essential in defending our bodies against harmful pathogens.
          Read More
          This shows tissue macrophages in a mouse brain
          FeaturedGeneticsNeuroscience
          ·April 22, 2022·4 min read

          New Discoveries About the Origin of the Brain’s Immune System

          New findings reveal phagocytes do not fully mature until after birth, contradicting previous assumptions that they mature during embryonic development.
          Read More
          This shows the outline of two heads covered in tree branches
          FeaturedNeurologyNeuroscienceOpen Neuroscience Articles
          ·November 24, 2021·3 min read

          New Link Between a Disrupted Body Clock and Inflammatory Diseases

          Study identifies a significant way in which a disrupted circadian clock drives inflammation in the body's immune cells.
          Read More
          This is an illustration of the spinal cord with the cells
          FeaturedNeurologyNeurosciencePain
          ·March 4, 2021·4 min read

          A New Cell Type Implicated in Chronic Pain and Inflammation

          MRC1+ macrophages are dysfunctional in animal models of neuropathic pain. Stimulating the expression of the anti-inflammatory protein CD163 reduced signs of neuroinflammation in the spinal cords of mice with neuropathic pain.
          Read More
          This shows marcophages
          FeaturedNeurologyNeuroscienceOpen Neuroscience Articles
          ·March 16, 2020·2 min read

          A new strategy for the management of inflammatory pain

          M2 macrophages can produce various endogenous opioids, such as endorphins, enkephalin, and dynorphin, which activate opioid receptors at the site of inflammation.
          Read More
          This shows cells from the study
          FeaturedGeneticsNeuroscienceOpen Neuroscience Articles
          ·February 4, 2020·5 min read

          Dopamine signals may guide migration of immune cells to infection sites

          Dopamine may play a role in activating immune cells to migrate in the early stages of infection.
          Read More
          This is a diagram of the gut
          FeaturedNeurologyNeuroscienceOpen Neuroscience Articles
          ·August 18, 2019·7 min read

          Whole body vibration shakes up microbiome, reducing inflammation in diabetes

          Whole-body vibration (WBV) therapy may be a way in which inflammation associated with diabetes can be controlled. WBV alters the microbiome, increasing levels of a bacterium that creates short-chain fatty acids, which help the body to better use glucose.
          Read More
          This shows macrophages in GBM tissue samples
          Brain CancerFeaturedNeurologyNeuroscience
          ·June 25, 2019·4 min read

          Scientists track brain tumor turncoats with advanced imaging

          Advanced imaging techniques visualize macrophages in brain tumors in mouse models of glioblastoma.
          Read More
          This show glioblastoma brain scans
          Brain CancerFeaturedGeneticsNeurologyNeuroscience
          ·June 10, 2019·5 min read

          Study finds macrophages’ pathway to nurture PTEN-deficient glioblastoma: Mouse study

          PTEN deficiency drives an increased expression of LOX. LOX attracts macrophages which protect gliobastoma brain cancer cells and provide growth factor support for the tumor, a new mouse study reveals.
          Read More
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          A 3D digital rendering showing a developing fetal brain connected by glowing neural pathways and floating DNA strands, surrounded by subtle immune cells.

          How Severe Illness During Pregnancy Alters Fetal Brain Development

          A 3D digital illustration of a human brain side-by-side comparison, highlighting the language centers glowing brightly and equally in both a younger and older brain, while executive function areas are dimmed in the older brain.

          Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

          Rejuvenation of Microglia by Youth Protein TIMP2 in the Aging Brain

          Youth Protein TIMP2 Restores Immune Function in the Aging Brain

          A multi-panel documentary photo. Left: A Black man sits alone on a locker room bench with his head down. Center: A Latino man sits withdrawn at a family kitchen table. Right: A White man looks thoughtfully at wellness pamphlets in a public waiting area. All convey isolation.

          Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

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