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macrophages

·June 12, 2023·8 min read

Cellular Custodians: ‘Big Eater’ Macrophages May Hold Key to Autoimmune Disease Treatment

The mysterious workings of tingible body macrophages (TBMs) have been substantially demystified. These TBMs, a subtype of macrophages within our lymph nodes, were found to devour antibody-producing B cells, a function essential in defending our bodies against harmful pathogens.

This shows tissue macrophages in a mouse brain

Featured Genetics Neuroscience

·April 22, 2022·4 min read

New Discoveries About the Origin of the Brain’s Immune System

New findings reveal phagocytes do not fully mature until after birth, contradicting previous assumptions that they mature during embryonic development.

This shows the outline of two heads covered in tree branches

Featured Neurology Neuroscience Open Neuroscience Articles

·November 24, 2021·3 min read

New Link Between a Disrupted Body Clock and Inflammatory Diseases

Study identifies a significant way in which a disrupted circadian clock drives inflammation in the body's immune cells.

This is an illustration of the spinal cord with the cells

Featured Neurology Neuroscience Pain

·March 4, 2021·4 min read

A New Cell Type Implicated in Chronic Pain and Inflammation

MRC1+ macrophages are dysfunctional in animal models of neuropathic pain. Stimulating the expression of the anti-inflammatory protein CD163 reduced signs of neuroinflammation in the spinal cords of mice with neuropathic pain.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 16, 2020·2 min read

A new strategy for the management of inflammatory pain

M2 macrophages can produce various endogenous opioids, such as endorphins, enkephalin, and dynorphin, which activate opioid receptors at the site of inflammation.

Featured Genetics Neuroscience Open Neuroscience Articles

·February 4, 2020·5 min read

Dopamine signals may guide migration of immune cells to infection sites

Dopamine may play a role in activating immune cells to migrate in the early stages of infection.

Featured Neurology Neuroscience Open Neuroscience Articles

·August 18, 2019·7 min read

Whole body vibration shakes up microbiome, reducing inflammation in diabetes

Whole-body vibration (WBV) therapy may be a way in which inflammation associated with diabetes can be controlled. WBV alters the microbiome, increasing levels of a bacterium that creates short-chain fatty acids, which help the body to better use glucose.

This shows macrophages in GBM tissue samples

Brain Cancer Featured Neurology Neuroscience

·June 25, 2019·4 min read

Scientists track brain tumor turncoats with advanced imaging

Advanced imaging techniques visualize macrophages in brain tumors in mouse models of glioblastoma.

Brain Cancer Featured Genetics Neurology Neuroscience

·June 10, 2019·5 min read

Study finds macrophages’ pathway to nurture PTEN-deficient glioblastoma: Mouse study

PTEN deficiency drives an increased expression of LOX. LOX attracts macrophages which protect gliobastoma brain cancer cells and provide growth factor support for the tumor, a new mouse study reveals.

This shows the outline of two heads and neurons

Featured Genetics Neurology Neuroscience

·May 6, 2019·3 min read

Detailed brain map uncovers hidden immune cells that may be involved in neurodegenerative disorders

Using mouse models, researchers have developed a comprehensive map of the brain's immune cells. The study found microglia in the choroid plexus showed a similar activation state as microglia that come into contact with Amyloid deposits.

Featured Neuroscience Open Neuroscience Articles Psychology

·September 14, 2018·4 min read

More Immune Cells in Brains of Those with Schizophrenia

A new study reports some people with schizophrenia have increased numbers of immune cells in their brains. Researchers say the immune cells may be producing inflammatory signals in those with the condition.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·August 21, 2018·4 min read

How the Body Clock Controls Inflammation

A new study sheds light on how the circadian clock controls inflammatory response. By understanding the link between inflammation and circadian rhythm, researchers believe it may be most effective to target specific conditions at certain times of the day. The findings may also explain why those who experience body clock disruptions are more susceptible to inflammatory conditions.

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macrophages

Cellular Custodians: ‘Big Eater’ Macrophages May Hold Key to Autoimmune Disease Treatment

New Discoveries About the Origin of the Brain’s Immune System

New Link Between a Disrupted Body Clock and Inflammatory Diseases

A New Cell Type Implicated in Chronic Pain and Inflammation

A new strategy for the management of inflammatory pain

Dopamine signals may guide migration of immune cells to infection sites

Whole body vibration shakes up microbiome, reducing inflammation in diabetes

Scientists track brain tumor turncoats with advanced imaging

Study finds macrophages’ pathway to nurture PTEN-deficient glioblastoma: Mouse study

Detailed brain map uncovers hidden immune cells that may be involved in neurodegenerative disorders

More Immune Cells in Brains of Those with Schizophrenia

How the Body Clock Controls Inflammation

Stickleback Fish Reveal Insights into Animal Decision-Making

AI-Enhanced Imaging: Probing Brain’s Visual Processing

High ‘Good Cholesterol’ Linked to Dementia Risk

Cannabis and Alcohol Co-use Impacts Adolescent Brain and Behavior

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