The 'shock and kill' therapeutic strategy for treating HIV could potentially cause harmful neuroinflammation, a new study reveals.
MRC1+ macrophages are dysfunctional in animal models of neuropathic pain. Stimulating the expression of the anti-inflammatory protein CD163 reduced signs of neuroinflammation in the spinal cords of mice with neuropathic pain.
Researchers investigate whether they can mobilize the immune system to help in the fight against Alzheimer's disease.
Using mouse models, researchers have developed a comprehensive map of the brain's immune cells. The study found microglia in the choroid plexus showed a similar activation state as microglia that come into contact with Amyloid deposits.
Researchers have discovered a method to engraft immune cells in the brains of lab mice without the use of radiation.
Researchers have been able to preserve cognition in mice exhibiting features of Alzheimer's disease.
A new study sheds light on how the circadian clock controls inflammatory response. By understanding the link between inflammation and circadian rhythm, researchers believe it may be most effective to target specific conditions at certain times of the day. The findings may also explain why those who experience body clock disruptions are more susceptible to inflammatory conditions.