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macrophages

The image shows pristine and CMC-coated Fe-MWNTs.

Brain Cancer Featured Neurology Open Neuroscience Articles

·December 12, 2014·2 min read

‘Trojan Horse’ Proteins Used to Target Hard to Reach Cancers

Using nanoparticles, researchers have discovered a way to target difficult to reach cancers.

Image shows brain cells from an SIV-infected macaque.

Featured Neurology Open Neuroscience Articles

·December 5, 2016·6 min read

“Shock and Kill” Strategy for Curing HIV May Endanger Patients’ Brains

The 'shock and kill' therapeutic strategy for treating HIV could potentially cause harmful neuroinflammation, a new study reveals.

This is an illustration of the spinal cord with the cells

Featured Neurology Neuroscience Pain

·March 4, 2021·4 min read

A New Cell Type Implicated in Chronic Pain and Inflammation

MRC1+ macrophages are dysfunctional in animal models of neuropathic pain. Stimulating the expression of the anti-inflammatory protein CD163 reduced signs of neuroinflammation in the spinal cords of mice with neuropathic pain.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 16, 2020·2 min read

A new strategy for the management of inflammatory pain

M2 macrophages can produce various endogenous opioids, such as endorphins, enkephalin, and dynorphin, which activate opioid receptors at the site of inflammation.

Image of an osteoclast, with bone below it, showing typical distinguishing characteristics: a large cell with multiple nuclei and a "foamy" cytosol.

Featured Neurology Open Neuroscience Articles

·September 21, 2015·5 min read

Alzheimer’s Drug Could Be Used to Treat Bone Loss

A new study reports a drug commonly used to treat Alzheimer's disease appears to effectively reduce bone loss and prevent fractures.

Image shows amyloid beta plaques surrounded by microglia.

Featured Neurology

·October 13, 2015·3 min read

Boosting the Brain’s Waste Disposal System to Help Fight Alzheimer’s

Researchers investigate whether they can mobilize the immune system to help in the fight against Alzheimer's disease.

Image shows dead cells in the SVZ of a mouse brain.

Featured Neuroscience Neuroscience Videos

·April 6, 2016·6 min read

Brain Guardians Remove Dying Neurons

A new study reports on how immune receptors clear dying and dysfunctional brain cells.

This shows the outline of two heads and neurons

Featured Genetics Neurology Neuroscience

·May 6, 2019·3 min read

Detailed brain map uncovers hidden immune cells that may be involved in neurodegenerative disorders

Using mouse models, researchers have developed a comprehensive map of the brain's immune cells. The study found microglia in the choroid plexus showed a similar activation state as microglia that come into contact with Amyloid deposits.

Featured Neurology

·April 11, 2018·5 min read

Discovery Could Let Doctors Customize Brain’s Immune Response to Disease

Researchers have discovered a method to engraft immune cells in the brains of lab mice without the use of radiation.

Featured Genetics Neuroscience Open Neuroscience Articles

·February 4, 2020·5 min read

Dopamine signals may guide migration of immune cells to infection sites

Dopamine may play a role in activating immune cells to migrate in the early stages of infection.

Featured Genetics Neurology

·July 7, 2015·5 min read

Enriched Blood Cells Help Preserve Cognition in Mice With Features of Alzheimer’s

Researchers have been able to preserve cognition in mice exhibiting features of Alzheimer's disease.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·August 21, 2018·4 min read

How the Body Clock Controls Inflammation

A new study sheds light on how the circadian clock controls inflammatory response. By understanding the link between inflammation and circadian rhythm, researchers believe it may be most effective to target specific conditions at certain times of the day. The findings may also explain why those who experience body clock disruptions are more susceptible to inflammatory conditions.

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