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hippocampus

·February 28, 2023·3 min read

Studying Brain Oscillations to Understand What Makes a Memory Stick

Memory formation requires higher-frequency ripples in the hippocampus and lower-frequency ripples in the parietal cortex. However, to make a memory stick, coordinated high-frequency ripples between the hippocampus and parietal cortex are required.

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·February 14, 2023·6 min read

Mysterious Brain Activity in Mice Watching a Movie Could Help Tackle Alzheimer’s and Improve AI

Tracking hippocampal neurons in mice as they watched a movie revealed novel ways to improve artificial intelligence and track neurological disorders associated with memory and learning deficits.

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·February 14, 2023·4 min read

Social Isolation Triggers Astrocyte-Mediated Deficits in Learning and Memory

During periods of social isolation, astrocytes in the brain become hyperactive. This suppresses circuit formation and memory formation. Reversing astrocyte hyperactivity can help mitigate memory deficits associated with social isolation.

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·February 13, 2023·5 min read

Study Reveals How CBD Counters Epileptic Seizures

Cannabidiol, or CBD, blocks the ability of lysophosphatidylinositol (LPI) to amplify neural signals in the hippocampus. LPI weakens the signals that counter seizures, further explaining the value of CBD to treat epilepsy.

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·February 9, 2023·5 min read

Disrupted Flow of Brain Fluid May Underlie Neurodevelopmental Disorders

Cerebral spinal fluid may play a key, underrecognized role in normal brain development and neurodevelopmental disorders.

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·January 27, 2023·3 min read

New Test Could Detect Alzheimer’s Disease 3.5 Years Before Clinical Diagnosis

A newly developed blood-based test reveals changes in hippocampal neurogenesis up to 3.5 years before a clinical diagnosis of Alzheimer's disease.

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·January 24, 2023·3 min read

New Clues About the Development of Epilepsy

The activation of dentate granule cells in the hippocampus plays a key role in alterations that occur during the development of post-traumatic epilepsy.

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·January 19, 2023·6 min read

Why Do We Remember Emotional Events Better Than Non-emotional Ones?

Researchers identified a mechanism within the brain that tags information with emotional association for enhanced memory. High-frequency brain waves in the amygdala and hippocampus are critical for enhancing emotional memories.

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·January 17, 2023·3 min read

High Fat Diet Activates Early Inflammation in Mouse Brains, Supports Link to Neurological Disease

High-fat diets promote early inflammatory responses in the brain via an immune pathway associated with diabetes and neurodegenerative diseases. The findings suggest a link between metabolic dysfunction and cognitive impairment.

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·January 17, 2023·7 min read

Smartphone App Can Significantly Improve Memory Recall

A new smartphone app, dubbed HippoCamera helps to significantly improve memory recall and could have applications for improving memory for those suffering from Alzheimer's disease. The app mimics the function of the hippocampus, constructing and maintaining memories. The app enhances biological memory encoding by boosting attention to daily events and consolidating them more distinctly.

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·January 13, 2023·3 min read

New Open-Source App for Precise Brain Mapping

A newly developed, open-source app that utilizes AI technology allows researchers to precisely map the structure of the hippocampus.

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·January 9, 2023·5 min read

Human-Approved Medication Brings Back ‘Lost’ Memories in Mice

Roflumilast, a drug commonly prescribed for the treatment of COPD and asthma helps retrieve learning memories following a period of sleep deprivation in mice.