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Genetics

·April 23, 2019·6 min read

More evidence that blood tests can detect the risk of Alzheimer’s

Neurofilament light protein in plasma may be a noninvasive biomarker for neurodegeneration associated with Alzheimer's disease.

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·April 23, 2019·5 min read

Short period of parental sexual contact prior to pregnancy increases offspring risk of schizophrenia

Study reports children born to couples who have been in relationships for three years or less may have an increased risk of schizophrenia.

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·April 22, 2019·8 min read

New insight into how obesity and insulin resistance can impair cognition

Adora2a mediating signaling in vascular endothelial cells disrupts the blood-brain barrier in obesity. This, researchers report, could be an underlying mechanism for synaptic plasticity and cognitive deficits in those with insulin resistance and obesity.

Autism Featured Genetics Neuroscience Psychology

·April 19, 2019·3 min read

High-risk genes for schizophrenia discovered

Study identifies 104 high-risk genes for schizophrenia. One gene considered high-risk is also suspected in the development of autism.

This shows VGLL3 expression in different skin samples

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·April 19, 2019·5 min read

Skin discovery may help explain why women get autoimmune diseases far more often than men

Skin cells may hold the key to explaining why women are more prone to developing autoimmune diseases, such as lupus than men. Researchers found women have more VGLL3 in their skin cells than men. VGLL3 pushes the immune system into overdrive, resulting in the 'self-attacking' autoimmune response, the mouse study revealed. Findings strongly implicate VGLL3 as a pivotal catalyst in sex-based autoimmunity.

This shows two people walking in the evening

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·April 18, 2019·6 min read

Two studies explore whether time of day can affect the body’s response to exercise

Two new studies report the time of day is a major modifier of exercise capacity, amplifying the impact exercise has on metabolic pathways and energy homeostasis. Evening exercise, researchers report, has the most productive effect.

This shows a graph detailing the effects of FL exposure to inflammation and immune response

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·April 18, 2019·3 min read

Study links fluorescent lighting to inflammation and immune response

Studies in fish and mice found genome-wide changes in the gene expression of patterns in the skin, brains and liver following exposure to white fluorescent light. Both the skin and brains exhibited increased inflammation and immune response following exposure.

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·April 18, 2019·5 min read

Study shows promise in repairing damaged myelin

A study in mouse models of multiple sclerosis demonstrates a compound called sobetirome promotes remyelination, and a derivative of the compound can penetrate the blood-brain barrier to enable a tenfold increase in infiltration to the CNS. Researchers are confident their research will translate from mice into humans, providing a new avenue of treatment for MS.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·April 17, 2019·4 min read

Gender identity leaves imprint on human brains

Gender identity, rather than sex, may cause the epigenome of the brain to differ in males and females.

Brain Cancer Featured Genetics Neuroscience Open Neuroscience Articles

·April 16, 2019·4 min read

Scientists ‘reverse engineer’ brain cancer cells to find new targets for treatment

Using CRISPR-Cas9 gene editing, researchers identified actionable pathways responsible for the growth of glioblastoma stem cells. By reverse engineering brain cancer cells, multiple potential new targets for cancer treatments have been uncovered.

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·April 16, 2019·3 min read

Researchers discover crucial link between brain and gut stem cells

The insulin-like growth factor II gene plays a critical role in adult stem cell maintenance of both the intestine and the brain. Findings suggest IGF-2 is essential for multiple stem cell types, including those implicated in cognitive function and renewing the lining of the small intestine.