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frontotemporal dementia

Blue is the nucleus, cyan is hUPF1, green is TDP43, red is the cell body in this image.

Featured Genetics Neurology

·June 8, 2015·4 min read

New Drug Target to Treat ALS Identified

Researchers have identified a cellular mechanism which may be targeted to treat ALS.

Scientists created a mouse model of ALS and FTD caused by mutations in the C9ORF72 gene. Credit: Courtesy of Petrucelli lab, Mayo Clinic, Jacksonville, Fla.

Featured Genetics

·May 22, 2015·4 min read

Scientists Create Mice with a Major Genetic Cause of ALS and FTD

Researchers believe mouse could provide a new platform for testing treatments for several neurodegenerative diseases.

This image shows a brain affected by FTD.

Featured Neurology

·April 23, 2015·4 min read

Intellectually Demanding Jobs Could Extend Life Span For Some With Early Onset Dementia

A new study reveals those who have more intellectually demanding careers could live longer after developing frontotemporal dementia.

Image shows the neurons with and without the mutation.

Featured Genetics Neurology

·March 23, 2015·2 min read

Novel Mechanism That Drives Progression of Frontotemporal Dementia Identified

Researchers uncover mechanism which controls synaptic growth and causes them to overgrow.

This image shows brain slice from a healthy brain and one from a brain affected by alzheimer's disease.

Featured Neurology

·September 29, 2014·3 min read

Protein that Causes Frontotemporal Dementia also Implicated in Alzheimer’s Disease

Low levels of progranulin shown to increase the formation of amyloid beta plaques and worsen memory deficits in mouse models of Alzheimer's disease.

This image shows a retina cross section from a healthy mouse.

Electrophysiology Featured Genetics

·August 25, 2014·3 min read

Changes in the Eye Can Predict Changes in the Brain

Researchers report retinal degeneration could be one of the earliest signs of FTD in people who have a genetic risk for the disorder.

The image shows the brain of an adult fruit fly.

Featured Genetics Neurology

·August 12, 2014·2 min read

Toxic Proteins Damage Nerve Cells

Researchers discover how a specific genetic mutation leads to neuronal damage associated with ALS and frontotemporal dementia.

This shows the difference between a healthy brain and one of an alzheimer's patient.

Featured Neurology

·February 25, 2014·2 min read

Brain Cell Activity Regulates Alzheimer’s Protein

A new study reports that increased neural activity boosts tau levels in the brain.

Featured Neurology

·November 6, 2013·2 min read

Speaking a Second Language May Delay Dementia

Researchers discover later onset of dementia in people who speak more than one language.

The image shows frontotemporal degeneration in the brain.

Featured Neurology Open Neuroscience Articles

·October 30, 2013·3 min read

RNA Build Up Linked to Dementia and Motor Neuron Disease

Researchers have identified a new toxic entity associated with genetically inherited forms of frontotemporal dementia and motor neuron disease.

This is a cross section MRI of a patient with ALS.

Featured Genetics Open Neuroscience Articles

·October 16, 2013·6 min read

‘Individualized’ Therapy for the Brain Targets Specific Gene Mutations Causing Dementia and ALS

Using neurons created from iPS cells derived from people with ALS, researchers develop a new drug which appears to halt the impact of the genetic mutations in some forms of ALS and dementia.

The image is a FDG-PET images show reduced glucose metabolism in temporal and parietal regions in patients with MCI and Alzheimer's disease.

Featured Neurology Open Neuroscience Articles

·June 26, 2013·6 min read

Promising Alzheimer’s ‘Drug’ Halts Memory Loss

Researchers discover a new class of experimental drug like small molecules show promise in targeting a brain enzyme to prevent early memory loss in Alzheimer's disease.

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frontotemporal dementia

New Drug Target to Treat ALS Identified

Scientists Create Mice with a Major Genetic Cause of ALS and FTD

Intellectually Demanding Jobs Could Extend Life Span For Some With Early Onset Dementia

Novel Mechanism That Drives Progression of Frontotemporal Dementia Identified

Protein that Causes Frontotemporal Dementia also Implicated in Alzheimer’s Disease

Changes in the Eye Can Predict Changes in the Brain

Toxic Proteins Damage Nerve Cells

Brain Cell Activity Regulates Alzheimer’s Protein

Speaking a Second Language May Delay Dementia

RNA Build Up Linked to Dementia and Motor Neuron Disease

‘Individualized’ Therapy for the Brain Targets Specific Gene Mutations Causing Dementia and ALS

Promising Alzheimer’s ‘Drug’ Halts Memory Loss

The Placenta May Decide Autism Vulnerability

Imaging Index Links Blood Flow to Cellular Architecture

Nighttime Light Exposure Linked to Sleep Loss in Schizophrenia

Eye-Blink Rate Predicts Cognitive Flexibility in Preschoolers

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