Researchers have identified how specific genetic mutations cause ALS. The pathway, they believe, may also be responsible for the development of frontotemporal dementia. Read More
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In all three types of frontotemporal dementia, researchers found the more the inflammation in each part of the brain, the more harmful the build-up of junk proteins. Read More
The protein beta-arrestin-2 increases tau tangle accumulation in Alzheimer's disease and frontotemporal dementia but interfering with the removal of excess tau from the brain. Read More
Gentamicin and G418, two aminoglycoside antibiotics, were effective at correcting genetic mutations associated with a specific form of frontotemporal dementia. The findings are promising for the treatment of frontotemporal dementia. Read More
Those with a genetic predisposition to frontotemporal dementia (FTD) can become resilient to the neurodegenerative disease by remaining physically and mentally active. Read More
Reducing activity in the anterior cingulate decreases empathetic responses in rats. The data suggests an observer shares the emotions of others as it enables them to prepare for danger. Read More
Extra virgin olive oil may protect against cognitive declines linked to tauopathy diseases, specifically frontotemporal dementia. Read More
The NLPR3 inflammasome and the inflammatory response it triggers play a critical role in the emergence of tau pathology. Read More
Researchers discovered increased inflammatory activity in a subgroup of patients with frontotemporal dementia. The increased inflammation was indicated by elevated levels of cytokines known to increase inflammatory response and decreased levels of IL-10, which reduces inflammation. The inflammation was associated with Parkinsonism's symptoms and rapid cognitive and functional decline. The study also revealed patients with FTD are less likely to develop cancer. Read More
A new brain mapping study allows for individual predictions of the progression of frontotemporal dementia. Read More
Researchers have identified the location of dysfunctional brain networks that lead to impaired sentence production and word-finding in primary progressive aphasia (PPA). PPA can occur in those with neurodegenerative diseases, such as frontotemporal dementia and Alzheimer's disease. Mapping the networks allows clinicians to apply non-invasive brain stimulation to potentially improve speech in those with PPA. Read More
A microscopy study revealed tau controls Fyn clustering in dendrites. The findings shed new light on how certain forms of dementia may occur. Read More
