FeaturedNeurologyNeuroscience·July 26, 2021·5 min readEarly Signs of Frontotemporal Dementia Found in Personalized Cerebral OrganoidsResearchers recreated the damage seen in frontotemporal dementia in brain organoid models. The study reveals an experimental drug designed to treat Crohn's disease may help prevent neuron death associated with FTD.Read More
FeaturedNeurologyNeuroscience·July 20, 2021·4 min readSpinal Fluid Biomarkers Detect Neurodegeneration and Alzheimer’s Disease in Living PatientsResearchers report Alzheimer's disease and other neurodegenerative disorders can be confirmed in living patients by specific biomarkers in cerebrospinal fluid.Read More
FeaturedNeurologyNeurosciencePsychology·April 12, 2021·5 min readProfound Loss of Pleasure Related to Early-Onset DementiaStudy links anhedonia, or the loss of pleasure, to the early onset of frontotemporal dementia. Neuroimaging revealed symptoms of anhedonia were marked by atrophy in the frontal and striatal brain areas of those with FTD.Read More
FeaturedNeurologyNeuroscience·February 17, 2021·3 min readWhite Matter Changes in Brain Found in Frontotemporal DementiaStudy reveals those with frontotemporal dementia have greater white matter hyperintensity than those with other forms of dementia. The amount of white matter hyperintensity was associated with the severity of FTD symptoms.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·September 8, 2020·5 min readInvestigational Drug Stops Toxic Proteins Tied To ALSc9ASO, an investigational ASO drug, targets the TDP-43 protein, reducing its buildup and decreasing neurological decline associated with ALS and FTD.Read More
FeaturedGeneticsNeurology·August 20, 2020·5 min readAutoimmune Diseases in ALS Patients Linked to Genetic MutationStudy reveals why some people with ALS are prone to developing autoimmune diseases. A genetic mutation that decreases the expression of C9orf72 causes the stimulation of interferon genes (STING) protein to become hyperactive. The hyperactivity leads to increased production of interferons. This can lead to systemic inflammation and the development of autoimmune diseases.Read More
FeaturedGeneticsNeurologyNeuroscience·June 10, 2020·4 min readNew genetic defect linked to ALSResearchers have identified how specific genetic mutations cause ALS. The pathway, they believe, may also be responsible for the development of frontotemporal dementia.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·March 17, 2020·5 min readInflammation in the brain linked to several forms of dementiaIn all three types of frontotemporal dementia, researchers found the more the inflammation in each part of the brain, the more harmful the build-up of junk proteins.Read More
FeaturedNeurologyNeuroscience·February 17, 2020·4 min readBeta-arrestin-2 increases neurotoxic tau driving frontotemporal dementiaThe protein beta-arrestin-2 increases tau tangle accumulation in Alzheimer's disease and frontotemporal dementia but interfering with the removal of excess tau from the brain.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·January 10, 2020·2 min readAntibiotics could be promising treatment for form of dementiaGentamicin and G418, two aminoglycoside antibiotics, were effective at correcting genetic mutations associated with a specific form of frontotemporal dementia. The findings are promising for the treatment of frontotemporal dementia.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·January 8, 2020·7 min readLifestyle choices could slow familial frontotemporal dementiaThose with a genetic predisposition to frontotemporal dementia (FTD) can become resilient to the neurodegenerative disease by remaining physically and mentally active.Read More
FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology·December 5, 2019·4 min readRats use same brain area as humans to empathize with othersReducing activity in the anterior cingulate decreases empathetic responses in rats. The data suggests an observer shares the emotions of others as it enables them to prepare for danger.Read More
