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frontotemporal dementia

Featured Neurology Neuroscience Open Neuroscience Articles

·November 25, 2019·5 min read

Study shows extra virgin olive oil staves off multiple forms of dementia in mice

Extra virgin olive oil may protect against cognitive declines linked to tauopathy diseases, specifically frontotemporal dementia.

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Featured Neurology Neuroscience

·November 20, 2019·4 min read

Inflammatory processes drive progression of Alzheimer’s and other brain diseases

The NLPR3 inflammasome and the inflammatory response it triggers play a critical role in the emergence of tau pathology.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·October 16, 2019·4 min read

Frontotemporal dementia is associated with alterations in immune system function

Researchers discovered increased inflammatory activity in a subgroup of patients with frontotemporal dementia. The increased inflammation was indicated by elevated levels of cytokines known to increase inflammatory response and decreased levels of IL-10, which reduces inflammation. The inflammation was associated with Parkinsonism's symptoms and rapid cognitive and functional decline. The study also revealed patients with FTD are less likely to develop cancer.

Featured Neurology Neuroscience

·October 14, 2019·6 min read

Dementia spreads via connected brain networks

A new brain mapping study allows for individual predictions of the progression of frontotemporal dementia.

This shows the location of the brain networks

Featured Neurology Neuroscience

·September 2, 2019·3 min read

Map of broken brain networks shows why people lose speech in language-based dementia

Researchers have identified the location of dysfunctional brain networks that lead to impaired sentence production and word-finding in primary progressive aphasia (PPA). PPA can occur in those with neurodegenerative diseases, such as frontotemporal dementia and Alzheimer's disease. Mapping the networks allows clinicians to apply non-invasive brain stimulation to potentially improve speech in those with PPA.

Featured Neurology Neuroscience Open Neuroscience Articles

·August 1, 2019·3 min read

Super-resolution microscopy sheds light on how dementia protein becomes dysfunctional

A microscopy study revealed tau controls Fyn clustering in dendrites. The findings shed new light on how certain forms of dementia may occur.

Featured Neurology Neuroscience Psychology

·June 14, 2019·4 min read

Moral emotions, a diagnostic tool for frontotemporal dementia?

Moral emotions are significantly more impaired than emotions without moral content in those with frontotemporal dementia (FTD). By contrast, those with Alzheimer's disease exhibit similar performance in both moral and extra-moral emotions as healthy subjects. The findings provide a novel biomarker for the diagnosis of FTD.

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Featured Neurology Neuroscience Open Neuroscience Articles

·June 11, 2019·4 min read

Memory Preserver: Researchers Develop Vaccine That Could Protect Against Alzheimer’s

Researchers have engineered a vaccine using virus-like particles that target Tau tangles in mouse models of Alzheimer's disease. Following the administration of the vaccine, the mice developed antibodies that cleared tau proteins, with the response lasting for a month. The mice also showed improvements in memory based tests and had less brain shrinkage than their peers who did not receive the vaccine. This suggests the vaccine prevented apoptosis. Researchers hope to move the vaccine to human clinical trials in the future.

Featured Neurology Neuroscience

·May 27, 2019·3 min read

Broken brain cells repaired in dementia mouse model

Chemically activating neurons and placing mice in stimulating environments reverses alterations and restores some neural connectivity in frontotemporal dementia. If translated into humans, the findings could help develop new treatments for fighting the effects of dementia in the elderly.

Featured Neurology Neuroscience Visual Neuroscience

·May 7, 2019·6 min read

Why visual stimulation may work in fight against Alzheimer’s: Mouse study

Inducing gamma oscillations with visual stimulation via a process known as gamma entrainment using sensory stimuli, or GENUS, was shown to reduce amyloid plaques and phosphorylated tau in mouse models of dementia. Providing GENUS daily during the early stages of neurodegeneration helps preserve neural and synaptic density across multiple brain areas and improves cognitive performance for learning and spatial memory tasks.

Featured Neuroscience Psychology

·January 8, 2019·5 min read

Researchers Identify Five Types of Insomnia

Researchers have identified five different subtypes of the sleep disorder insomnia, including difficulty falling asleep and early morning awakening. The study reports insomnia subtypes may be identified by examining personality traits of sufferers.

Featured Genetics Neurology Open Neuroscience Articles

·December 13, 2018·6 min read

New Genetic Clues to Frontotemporal Dementia

Study reports a mutation in a single gene that causes hereditary frontotemporal dementia makes it harder for neurons to communicate, leading to neurodegeneration.

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frontotemporal dementia

Study shows extra virgin olive oil staves off multiple forms of dementia in mice

Inflammatory processes drive progression of Alzheimer’s and other brain diseases

Frontotemporal dementia is associated with alterations in immune system function

Dementia spreads via connected brain networks

Map of broken brain networks shows why people lose speech in language-based dementia

Super-resolution microscopy sheds light on how dementia protein becomes dysfunctional

Moral emotions, a diagnostic tool for frontotemporal dementia?

Memory Preserver: Researchers Develop Vaccine That Could Protect Against Alzheimer’s

Broken brain cells repaired in dementia mouse model

Why visual stimulation may work in fight against Alzheimer’s: Mouse study

Researchers Identify Five Types of Insomnia

New Genetic Clues to Frontotemporal Dementia

Reducing Visceral Fat Protects the Brain for Decades

Brain-First Hypothesis: Rethinking the Cambrian Explosion

Beyond the Gym: Why Your Brain Craves Creatine

Brain Switch for Action and Stress Identified

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