frontotemporal dementia

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frontotemporal dementia

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·October 16, 2019·4 min read

Frontotemporal dementia is associated with alterations in immune system function

Researchers discovered increased inflammatory activity in a subgroup of patients with frontotemporal dementia. The increased inflammation was indicated by elevated levels of cytokines known to increase inflammatory response and decreased levels of IL-10, which reduces inflammation. The inflammation was associated with Parkinsonism's symptoms and rapid cognitive and functional decline. The study also revealed patients with FTD are less likely to develop cancer. Read More

Featured Neurology Neuroscience

·October 14, 2019·6 min read

Dementia spreads via connected brain networks

A new brain mapping study allows for individual predictions of the progression of frontotemporal dementia. Read More

This shows the location of the brain networks

Featured Neurology Neuroscience

·September 2, 2019·3 min read

Map of broken brain networks shows why people lose speech in language-based dementia

Researchers have identified the location of dysfunctional brain networks that lead to impaired sentence production and word-finding in primary progressive aphasia (PPA). PPA can occur in those with neurodegenerative diseases, such as frontotemporal dementia and Alzheimer's disease. Mapping the networks allows clinicians to apply non-invasive brain stimulation to potentially improve speech in those with PPA. Read More

Featured Neurology Neuroscience Open Neuroscience Articles

·August 1, 2019·3 min read

Super-resolution microscopy sheds light on how dementia protein becomes dysfunctional

A microscopy study revealed tau controls Fyn clustering in dendrites. The findings shed new light on how certain forms of dementia may occur. Read More

Featured Neurology Neuroscience Psychology

·June 14, 2019·4 min read

Moral emotions, a diagnostic tool for frontotemporal dementia?

Moral emotions are significantly more impaired than emotions without moral content in those with frontotemporal dementia (FTD). By contrast, those with Alzheimer's disease exhibit similar performance in both moral and extra-moral emotions as healthy subjects. The findings provide a novel biomarker for the diagnosis of FTD. Read More

This shows a virus like protein structure

Featured Neurology Neuroscience Open Neuroscience Articles

·June 11, 2019·4 min read

Memory Preserver: Researchers Develop Vaccine That Could Protect Against Alzheimer’s

Researchers have engineered a vaccine using virus-like particles that target Tau tangles in mouse models of Alzheimer's disease. Following the administration of the vaccine, the mice developed antibodies that cleared tau proteins, with the response lasting for a month. The mice also showed improvements in memory based tests and had less brain shrinkage than their peers who did not receive the vaccine. This suggests the vaccine prevented apoptosis. Researchers hope to move the vaccine to human clinical trials in the future. Read More

Featured Neurology Neuroscience

·May 27, 2019·3 min read

Broken brain cells repaired in dementia mouse model

Chemically activating neurons and placing mice in stimulating environments reverses alterations and restores some neural connectivity in frontotemporal dementia. If translated into humans, the findings could help develop new treatments for fighting the effects of dementia in the elderly. Read More

Featured Neurology Neuroscience Visual Neuroscience

·May 7, 2019·6 min read

Why visual stimulation may work in fight against Alzheimer’s: Mouse study

Inducing gamma oscillations with visual stimulation via a process known as gamma entrainment using sensory stimuli, or GENUS, was shown to reduce amyloid plaques and phosphorylated tau in mouse models of dementia. Providing GENUS daily during the early stages of neurodegeneration helps preserve neural and synaptic density across multiple brain areas and improves cognitive performance for learning and spatial memory tasks. Read More

Featured Neuroscience Psychology

·January 8, 2019·5 min read

Researchers Identify Five Types of Insomnia

Researchers have identified five different subtypes of the sleep disorder insomnia, including difficulty falling asleep and early morning awakening. The study reports insomnia subtypes may be identified by examining personality traits of sufferers. Read More

Featured Genetics Neurology Open Neuroscience Articles

·December 13, 2018·6 min read

New Genetic Clues to Frontotemporal Dementia

Study reports a mutation in a single gene that causes hereditary frontotemporal dementia makes it harder for neurons to communicate, leading to neurodegeneration. Read More

Featured Genetics Neurology

·December 3, 2018·6 min read

Researchers Pinpoint Genes Tied to Dementia

Researchers have identified two major groups of genes involved in mutations that result in an overproduction of tau. The findings could offer new avenues for treatments to slow the progression of dementia. Read More