The Molecular Link Between Aging and Neurodegeneration
A new study provides new clues for the links between aging and neurodegenerative diseases. ... Read More...
frontotemporal dementia
Understanding the Origins of Alzheimer’s Disease
Researchers investigate the role the BMI1 gene plays in the onset and development of Alzheimer's disease. The study reports the loss of BMI1 triggers and increased production of amyloid beta and decreases neural ability to eliminate the protein.... Read More...
Tau Mutations May Increase Cancer Risk
A new study reports tau mutations, commonly associated with neurodegenerative diseases like dementia, may also increase the risk of developing cancers. ... Read More...
ALS and FTD Share Genetic Link
A new study links common genetic variants to both ALS and frontotemporal dementia. The findings could help in the development of treatment strategies for both disorders, researchers report.... Read More...
Focusing on Early Stage of Illness May Be Key to Treating ALS
A new study reveals many inhibitory neurons are lost in early phases of ALS and FTD development. The findings show a contrast to other neurodegenerative diseases where excitatory neurons are lost early in the disorders.... Read More...
CRISPR Helps Find New Genetic Suspects Behind ALS and FTD
Using CRISPR, researchers have identified a new set of genes that may be implicated in both ALS and frontotemporal dementia.... Read More...
The Toxic Relationship Between ALS and Frontotemporal Dementia
Researchers report the C9ORF72 genetic mutation can lead to toxicity in neurons, causing 10 percent of all ALS cases and 10 percent of FTD cases. ... Read More...
Genetic Mutations Cause ‘Vicious Cycle’ in Most Common Form of ALS
Researchers reveal a repeat element in the DNA of C9orf72 gene becomes toxic when faced with starvation, toxins and viral infection. ... Read More...
Deadly Combination in Neurodegenerative Diseases Revealed
A new mouse model has been developed that captures the pathology of sporadic neurodegenerative diseases.... Read More...
New Insight Into How Brain Cells Die in Alzheimer’s and FTD
A gene that is critical in early stages of embryonic development appears to also play a key role in neurodegenerative diseases like Alzheimer's and frontotemporal dementia, researchers say.... Read More...
Fundamental ALS Pathology Discovered
Researchers have identified a genetic mutation associated with both ALS and frontotemporal dementia.... Read More...
Granulins Are Brain Treasure, Not Trash
A new tool allows researchers to observe granulins inside cells. ... Read More...