Krill oil protects dopaminergic neurons from age-related degeneration, decreases alpha-synuclein aggregation, and improves dopamine-dependent cognition and behavior in lab models of Parkinson's disease.
Study reveals the mechanism of the nucleus accumbens for mediating reward and aversion.
Researchers shed light on how different SSRI antidepressants may work to help fight symptoms of depression in the brain.
Exercise can help improve mood and overall symptoms of those who suffer from seasonal affective disorder (SAD).
The dopamine system helps the brain anticipate the occurrence and duration of unpleasant events, but without taking errors into account.
A display of defensive behaviors, when faced with an aggressive mouse, predicted a smaller mouse's ability to become resilient following a traumatic event. Stimulating dopamine production in defensive smaller mice induced resilience.
Study reveals gender-specific differences in the dopamine-regulated signaling pathways in B-cells, concluding dopamine may have a pro-inflammatory effect in female rheumatoid arthritis patients.
Exploring a new environment helps boost dopamine levels which are projected to the hippocampus, decreasing the threshold for learning. However, in older people, the novelty of a new environment doesn't boost memory as much as it does in younger people.
The direct phosphorylation of KCNQ2 by ERK occurs through the activation of the dopamine signaling pathway in the nucleus accumbens of mice.
Psychostimulants increase dopamine levels, enhancing task-relevant cortical signals by acting on the striatum and the difference in dopamine synthesis capacity in the striatum explains the variability in the drugs' cognitive effects.
Addiction occurs as a result of the reward system becoming overwhelmed in a way that leads to chronic and permanent alterations in the brain.
Researchers successfully turned skin cells from Parkinson's patients into dopaminergic neurons by introducing a combination of neural-inducing genes into the skin cells.