Female mice show effects of the DAT mutation in brain regions unaffected in males, and vice versa. The findings reveal surprising differences in dopamine synapses between males and females controlling attention, pleasure, and motivation
A new hypothesis suggests when people are awake during the biological circadian night there are neurophysiological changes in the brain that alters the way in which we interact with the world, especially when it comes to impulse control, information processing, and reward processing.
Dopamine in the cerebellum helps regulate social behaviors via its action on D2 receptors. Changes in D2 levels in Purkinje cells alter sociability and preference for social novelty without affecting motor function.