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CNS

Featured Genetics Neurology Neuroscience

·October 22, 2024·5 min read

Gene Discovery Boosts CNS Regeneration for Spinal Injury Repair

A recent study highlights a novel gene, lipin1, that regulates axon regeneration in the central nervous system, offering new hope for treating spinal cord injuries. The research shows that inhibiting lipin1 enhances lipid metabolism in neurons, activating crucial pathways like mTOR and STAT3 that promote nerve regeneration.

Featured Neurology Neuroscience

·March 20, 2024·4 min read

Astrocytes Remember: A New Layer of Immune Memory Uncovered

Astrocytes, traditionally non-immune cells within the central nervous system, possess the ability to develop an immune memory, responding more vigorously to subsequent immune challenges. This groundbreaking study reveals that through an epigenetic mechanism involving the enzymes p300 and ATP-citrate lyase (ACLY), astrocytes enhance their pro-inflammatory responses, a trait similar to the immune memory seen in adaptive immunity.

Featured Genetics Neuroscience

·February 26, 2024·7 min read

Stem Cells Model of Early Human Central Nervous System Created

Researchers have developed the first stem cell culture method that accurately models the early stages of the human central nervous system (CNS), marking a significant breakthrough in neuroscience. This 3D human organoid system simulates the development of the brain and spinal cord, offering new possibilities for studying human brain development and diseases.

Featured Genetics Neurology Neuroscience

·January 30, 2023·5 min read

How Our Brains Turn Into Smarter Disease Fighters

CRISPR gene editing created the G795A amino acid which was introduced to microglia derived from human stem cells. Researchers were able to transplant the donor microglia immune cells into humanized rodent models while administering an FDA-approved cancer drug called pexidartinib. The inclusion of the amino acid cause the donated microglia to thrive and resist the drug, while the host microglia died. The findings open the door for new methods of using microglia to treat a range of neurodegenerative disorders.

Featured Neuroscience

·January 25, 2023·3 min read

Mechanical Forces in the Nervous System Play a Corrective Role

Synaptic pruning occurs as a result of mechanical tearing, a new study reveals.

Featured Neuroscience Open Neuroscience Articles

·November 28, 2022·7 min read

Unique Features of Octopus Create an Entirely New Way of Designing a Nervous System

Researchers discovered a structure within the octopus nervous system by which the intramuscular nerve cords, which help the cephalopod to sense its arm movements, connect arms on the opposite side of the animal.

Featured Neuroscience Open Neuroscience Articles

·November 10, 2022·5 min read

How Squid and Octopus Get Their Big Brains

Neural stem cells of cephalopods act in a similar way to those of vertebrates during nervous system development.

Featured Neuroscience Open Neuroscience Articles

·October 5, 2022·5 min read

Multiple Health Benefits of Chocolate, Red Wine, and Apples When Consumed in the Right Amounts

Optimal intake of B-type procyanidins, a class of polyphenols found in apples, cocoa, and red wine, is linked to metabolic and the hormesis of hemodynamic responses.

This shows a 3d map of the brain's drainage system

Featured Neuroscience

·August 2, 2022·3 min read

The Brain’s Drainage System in 3D

The CSF drainage pathways are similar between mice and humans, researchers discovered.

Featured Neuroscience

·July 28, 2022·4 min read

Study Provides Better Insight Into the Vagus Nerve’s Link to the Brain

Using stimulation, researchers found a direct connection between the vagus nerve and learning centers of the brain. Vagus nerve stimulation, they discovered, increases learning in a healthy nervous system.

Featured Genetics Neurology Neuroscience

·June 22, 2022·4 min read

ALS May Be Linked to Both the Immune and Central Nervous Systems

Researchers discovered both immune system and central nervous system dysfunction in animal models and people with ALS4, a genetic, juvenile, and slow-progressing form of ALS.