At the site of injury, nerves release a protein called CXCL12 which attracts growing nerve fibers and keeps them trapped in place. This prevents the nerve fibers from growing in the correct direction to bridge the injury site.
IgA cells that originate in the gut play a role appear to have neuroprotective properties against diseases associated with neuroinflammation, such as meningitis.
Researchers have devised techniques that allowed them to successfully replace dysfunctional microglia.
Tufts researchers have developed neurotransmitter-lipid hybrids that help transport therapeutic drugs and gene editing proteins across the blood-brain barrier in mice.
Damage to the nasal epithelium increases the risk of bacteria entering into the brain, potentially resulting in long-term health problems.
Enhancing mitochondrial transportation and cellular energetics could help promote regeneration and function following spinal cord injury.
A global knockout of the thrombin receptor PAR1 accelerates myelin development. The findings could help with the development of treatments for diseases associated with demyelination, like multiple sclerosis.
Lewy body disorders, including Parkinson's disease and Lewy body dementia, comprise of two distinct subtypes. One subtype originates in the peripheral nervous system (PNS) of the gut and spreads to the brain. The other originates in the brain, or enters the brain via the olfactory system, before spreading to the brainstem and PNS.
People with functional dizziness do not appear to process sensory-motor impression correctly. Instead, they rely on a stored memory model which no longer matches immediate reality.